Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Safety and Effectiveness of Moderate Sedation for Radiologic Non-Vascular Intervention

  • Kim, Tae-Hoon (Department of Radiology, Dankook University Hospital)
  • Published : 2006.06.30
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Abstract

Objective: The purpose of this study was to prospectively characterize the safety and effectiveness of moderate sedation/analgesia for performing radiologic non-vascular abdominal intervention. Materials and Methods: During a 3-month period, a total of 63 adult patients with a mean age of 64 years (range: 27-82) underwent moderate sedation for 72 radiologic non-vascular interventional procedures. A combination of fentanyl citrate and midazolam hydrochloride, based on the patient's body weight, was intravenously administered until th'8 patient was drowsy and tranquil. The adverse events associated with this moderate sedation were assessed. The visual analog scale format was used to measure the subjective feelings of the patient's pre-procedural anxiety and intraprocedural pain. Results: The mean total dose per kilogram of body weight of fentanyl used in PTBD was $1.148{\mu}g$, it was $1.157{\mu}g$ for PTGBD, $1{\mu}g$ for AD, $1{\mu}g$ for PCN, $1.641{\mu}g$ for TDC, $1{\mu}g$ for DJS, $2{\mu}g$ for BS, $1{\mu}g$ for GS and $2{\mu}g$ for RFA. The mean total dose per kilogram of body weight of midazolam was 0.035mg in PTBD, PTGBD, AD, PCN, DJS, GS and RFA, 0.039 mg in TDC, and 0.043 mg in BS. A temporary reduction of systolic blooej pressure to less than 80mmHg was observed during 5 procedures (6.9%), whereas a temporary elevation of systolic blood pressure above 150mmHg was observed during 10 procedures (13.8%). A reduction of arterial oxygen saturation to less than 90% was observed during 14 procedures (19.4%). None of the patients required pharmacologic reversal agents or cardiopulmonary resuscitation. The mean anxiety score recorded before all procedures was 5.2 (distressing). The mean pain score during the procedure, which was recorded after all procedures, was 2.9 (mild). Conclusion: Moderate sedation allows performance of safe and effective radiologic non-vascular intervention, and it is also easy for an interventional radiologist to use. The patients should be continuously monitored to check their vital signs and arterial oxygen saturation during the procedures.

Keywords

References

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