흰쥐에 삽입된 인공성형삽입물의 생체내 물리, 조직학적 변화의 비교

Comparison of Physical & Histological Change of Alloplastic Implants after Implantation in Rat

  • 김성남 (전남대학교 의과대학 성형외과학교실) ;
  • 노복균 (전남대학교 의과대학 성형외과학교실) ;
  • 김의식 (전남대학교 의과대학 성형외과학교실) ;
  • 황재하 (전남대학교 의과대학 성형외과학교실) ;
  • 김광석 (전남대학교 의과대학 성형외과학교실) ;
  • 이삼용 (전남대학교 의과대학 성형외과학교실) ;
  • 조백현 (벨라성형외과)
  • Kim, Sung Nam (Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School) ;
  • Noh, Bok Kyun (Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School) ;
  • Kim, Eui Sik (Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School) ;
  • Hwang, Jae Ha (Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School) ;
  • Kim, Kwang Seog (Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School) ;
  • Lee, Sam Yong (Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School) ;
  • Cho, Bek Hyun (Bella Plastic Surgery Clinic)
  • 투고 : 2005.10.21
  • 발행 : 2006.03.10

초록

Augmentation rhinoplasty is one of the most popular aesthetic procedure in Asians. Numerous alloplastic implants have been used until now, but no accurate comparative analysis about the implant materials has been reported yet. This study in animal model was designed to determine the safety and effectiveness of various implant materials in augmentation rhinoplasty. The $15{\times}15{\times}2mm$ sized square shaped plate of $Gore-Tex^{(R)}$, silicone rubber, and $15{\times}15{\times}1.5mm$ sized $Medpor^{(R)}$ were implanted under panniculus carnosus of the abdomen wall of rat. And tissue specimens including the implant and surrounding soft tissue were obtained by en bloc excision in 6 months after implantation. The implants were estimated in weight and volume, and also the specimens were examined grossly and microscopically. The results revealed that increase of average weight 26.9%, decrease of average volume 55.4% in $Gore-Tex^{(R)}$ implant, increase of each average weight and volume 62.6%, 8.7% in $Medpor^{(R)}$ implant and very slight increase of both average weight and volume 4.7%, 1.1% in silicone rubber implant. Grossly, the $Gore-Tex^{(R)}$ was deformed, $Medpor^{(R)}$ was strongly adherent to surrounding soft tissue and the silicone rubber was well encapsulated and easily peeled off. Microscopically, silicone rubber showed foreign body reaction slightly and there were no inflammatory responses in all alloplastic implants. In our study, silicone rubber showed very proper alloplastic features for augmentation rhinoplasty due to causing no inflammatory response, no physical change, and no deformity.

키워드

참고문헌

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