Acknowledgement
Supported by : Korean Ministry of Science and Technology, National Institutes of Health
References
- Albert, A. P. (2004) Activation of TRPC6 channel proteins: evidence for an essential role of phosphorylation. J. Physiol. 561, 354 https://doi.org/10.1113/jphysiol.2004.077131
- Allen, P. D. (2002) Leaky 'feet' and sudden death. Circ. Res. 91, 181-182 https://doi.org/10.1161/01.RES.0000030194.38795.86
- Allen, P. D. (2003) Not all sudden death is the same. Circ. Res. 93, 484-486 https://doi.org/10.1161/01.RES.0000093184.27194.42
-
Anderson, K. and Meissner, G. (1995) T-tubule depolarizationinduced SR
$Ca^{2+}$ release is controlled by dihydropyridine receptor- and$Ca^{2+}$ -dependent mechanisms in cell homogenates from rabbit skeletal muscle. J. Gen. Physiol. 105, 363-383 https://doi.org/10.1085/jgp.105.3.363 - Antoniotti, S., Lovisolo, D., Fiorio Pla, A., and Munaron, L. (2002) Expression and functional role of bTRPC1 channels in native endothelial cells. FEBS Lett. 510, 189-195 https://doi.org/10.1016/S0014-5793(01)03256-2
- Avila, G., Lee, E. H., Perez, C. F., Allen, P. D., and Dirksen, R. T. (2003) FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes. J. Biol. Chem. 278, 22600-22608 https://doi.org/10.1074/jbc.M205866200
- Balshaw, D. M., Yamaguchi, N., and Meissner, G. (2002) Modulation of intracellular calcium-release channels by calmodulin. J. Membr. Biol. 185, 1-8 https://doi.org/10.1007/s00232-001-0111-4
- Barac, Y. D., Zeevi-Levin, N., Yaniv, G., Reiter, I., Milman, F., et al. (2005) The 1,4,5-inositol trisphosphate pathway is a key component in Fas-mediated hypertrophy in neonatal rat ventricular myocytes. Cardiovasc. Res. 68, 75-86 https://doi.org/10.1016/j.cardiores.2005.05.015
- Beech, D. J., Muraki, K., and Flemming, R. (2004) Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP. J. Physiol. 559, 685-706 https://doi.org/10.1113/jphysiol.2004.068734
- Berridge, M. J., Bootman, M. D., and Roderick, H. L. (2003) Calcium signalling: dynamics, homeostasis and remodelling. Nat. Rev. Mol. Cell Biol. 4, 517-529 https://doi.org/10.1038/nrm1155
- Bezzerides, V. J., Ramsey, I. S., Kotecha, S., Greka, A., and Clapham, D. E. (2004) Rapid vesicular translocation and insertion of TRP channels. Nat. Cell Biol. 6, 709-720 https://doi.org/10.1038/ncb1150
- Block, B. A., Imagawa, T., Campbell, K. P., and Franzini- Armstrong, C. (1988) Structural evidence for direct interaction between the molecular components of the transverse tubule/ sarcoplasmic reticulum junction in skeletal muscle. J. Cell Biol. 107, 2587-2600 https://doi.org/10.1083/jcb.107.6.2587
- Brady, A. J. (1964) Excitation and excitation-contraction coupling in cardiac muscle. Annu. Rev. Physiol. 26, 341-356 https://doi.org/10.1146/annurev.ph.26.030164.002013
- Brandt, N. R., Caswell, A. H., Wen, S. R., and Talvenheimo, J. A. (1990) Molecular interactions of the junctional foot protein and dihydropyridine receptor in skeletal muscle triads. J. Membr. Biol. 113, 237-251 https://doi.org/10.1007/BF01870075
- Brandt, A., Schleithoff, L., Jurkat-Rott, K., Klingler, W., Baur, C., et al. (1999) Screening of the ryanodine receptor gene in 105 malignant hyperthermia families: novel mutations and concordance with the in vitro contracture test. Hum. Mol. Genet. 8, 2055-2062 https://doi.org/10.1093/hmg/8.11.2055
- Brillantes, A. B., Ondrias, K., Scott, A., Kobrinsky, E., Ondriasova, E., et al. (1994) Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein. Cell 77, 513-523 https://doi.org/10.1016/0092-8674(94)90214-3
-
Brough, G. H., Wu, S., Cioffi, D., Moore, T. M., Li, M., et al. (2001) Contribution of endogenously expressed Trp1 to a
$Ca^{2+}$ -selective, store-operated$Ca^{2+}$ entry pathway. FASEB J. 15, 1727-1738 https://doi.org/10.1096/fj.01-0108com - Calviello, G. and Chiesi, M. (1989) Rapid kinetic analysis of the calcium-release channels of skeletal muscle sarcoplasmic reticulum: the effect of inhibitors. Biochemistry 28, 1301-1306 https://doi.org/10.1021/bi00429a053
- Cannell, M. B., Cheng, H., and Lederer, W. J. (1995) The control of calcium release in heart muscle. Science 268, 1045-1049 https://doi.org/10.1126/science.7754384
- Carter, S., Colyer, J., and Sitsapesan, R. (2006) Maximum phosphorylation of the cardiac ryanodine receptor at serine-2809 by protein kinase A produces unique modifications to channel gating and conductance not observed at lower levels of phosphorylation. Circ. Res. (in press)
- Chamberlain, B. K., Volpe, P., and Fleischer, S. (1984a) Calciuminduced calcium release from purified cardiac sarcoplasmic reticulum vesicles. General characteristics. J. Biol. Chem. 259, 7540-7546
- Chamberlain, B. K., Volpe, P., and Fleischer, S. (1984b) Inhibition of calcium-induced calcium release from purified cardiac sarcoplasmic reticulum vesicles. J. Biol. Chem. 259, 7547-7553
- Chu, A., Sumbilla, C., Inesi, G., Jay, S. D., and Campbell, K. P. (1990) Specific association of calmodulin-dependent protein kinase and related substrates with the junctional sarcoplasmic reticulum of skeletal muscle. Biochemistry 29, 5899-5905 https://doi.org/10.1021/bi00477a003
- Clapham, D. E. (2003) TRP channels as cellular sensors. Nature 426, 517-524 https://doi.org/10.1038/nature02196
- Collins, J. H. (1991) Sequence analysis of the ryanodine receptor: possible association with a 12K, FK506-binding immunophilin/ protein kinase C inhibitor. Biochem. Biophys. Res. Commun. 178, 1288-1290 https://doi.org/10.1016/0006-291X(91)91033-9
- Cosens, D. J. and Manning, A. (1969) Abnormal electroretinogram from a Drosophila mutant. Nature 224, 285-287 https://doi.org/10.1038/224285a0
- Deufel, T., Sudbrak, R., Feist, Y., Rubsam, B., Du Chesne, I., et al. (1995) Discordance, in a malignant hyperthermia pedigree, between in vitro contracture-test phenotypes and haplotypes for the MHS1 region on chromosome 19q12-13.2, comprising the C1840T transition in the RYR1 gene. Am. J. Hum. Genet. 56, 1334-1342
- Dietrich, A., Mederosy Schnitzler, M., Emmel, J., Kalwa, H., Hofmann, T., et al. (2003) N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity. J. Biol. Chem. 278, 47842-47852 https://doi.org/10.1074/jbc.M302983200
- Dietrich, A., Mederos, Y. S. M., Gollasch, M., Gross, V., Storch, U., et al. (2005) Increased vascular smooth muscle contractility in TRPC6-/- mice. Mol. Cell. Biol. 25, 6980-6989 https://doi.org/10.1128/MCB.25.16.6980-6989.2005
- Dirksen, R. T. (2002) Bi-directional coupling between dihydropyridine receptors and ryanodine receptors. Front. Biosci. 7, d659-670 https://doi.org/10.2741/dirksen
- Donoso, P. and Hidalgo, C. (1993) pH-sensitive calcium release in triads from frog skeletal muscle. Rapid filtration studies. J. Biol. Chem. 268, 25432-25438
-
Du, G. G., Sandhu, B., Khanna, V. K., Guo, X. H., and MacLennan, D. H. (2002) Topology of the
$Ca^{2+}$ release channel of skeletal muscle sarcoplasmic reticulum (RyR1). Proc. Natl. Acad. Sci. USA 99, 16725-16730 - Fabiato, A. (1983) Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. Am. J. Physiol. 245, C1-14
- Feng, W., Tu, J., Yang, T., Vernon, P. S., Allen, P. D., et al. (2002) Homer regulates gain of ryanodine receptor type 1 channel complex. J. Biol. Chem. 277, 44722-44730 https://doi.org/10.1074/jbc.M207675200
-
Fleischer, S., Ogunbunmi, E. M., Dixon, M. C., and Fleer, E. A. (1985) Localization of
$Ca^{2+}$ release channels with ryanodine in junctional terminal cisternae of sarcoplasmic reticulum of fast skeletal muscle. Proc. Natl. Acad. Sci. USA 82, 7256- 7259 - Flemming, R., Xu, S. Z., and Beech, D. J. (2003) Pharmacological profile of store-operated channels in cerebral arteriolar smooth muscle cells. Br. J. Pharmacol. 139, 955-965 https://doi.org/10.1038/sj.bjp.0705327
- Franzini-Armstrong, C. and Jorgensen, A. O. (1994) Structure and development of E-C coupling units in skeletal muscle. Annu. Rev. Physiol. 56, 509-534 https://doi.org/10.1146/annurev.ph.56.030194.002453
- Franzini-Armstrong, C. and Kish, J. W. (1995) Alternate disposition of tetrads in peripheral couplings of skeletal muscle. J. Muscle Res. Cell Motil. 16, 319-324 https://doi.org/10.1007/BF00121140
-
Freichel, M., Suh, S. H., Pfeifer, A., Schweig, U., Trost, C., et al. (2001) Lack of an endothelial store-operated
$Ca^{2+}$ current impairs agonist-dependent vasorelaxation in TRP4-/- mice. Nat. Cell Biol. 3, 121-127 https://doi.org/10.1038/35055019 - Freichel, M., Philipp, S., Cavalie, A., and Flockerzi, V. (2004) TRPC4 and TRPC4-deficient mice. Novartis Found. Symp. 258, 189-199
- Freichel, M., Vennekens, R., Olausson, J., Stolz, S., Philipp, S. E., et al. (2005) Functional role of TRPC proteins in native systems: implications from knockout and knock-down studies. J. Physiol. 567, 59-66 https://doi.org/10.1113/jphysiol.2005.092999
- Fuentes, O., Valdivia, C., Vaughan, D., Coronado, R., and Valdivia, H. H. (1994) Calcium-dependent block of ryanodine receptor channel of swine skeletal muscle by direct binding of calmodulin. Cell Calcium 15, 305-316 https://doi.org/10.1016/0143-4160(94)90070-1
- Gailly, P. (2002) New aspects of calcium signaling in skeletal muscle cells: implications in Duchenne muscular dystrophy. Biochim. Biophys. Acta 1600, 38-44 https://doi.org/10.1016/S1570-9639(02)00442-9
- Gailly, P. and Colson-Van Schoor, M. (2001) Involvement of trp-2 protein in store-operated influx of calcium in fibroblasts. Cell Calcium 30, 157-165 https://doi.org/10.1054/ceca.2001.0221
- Garcia, R. L. and Schilling, W. P. (1997) Differential expression of mammalian TRP homologues across tissues and cell lines. Biochem. Biophys. Res. Commun. 239, 279-283 https://doi.org/10.1006/bbrc.1997.7458
-
Gechtman, Z., Orr, I., and Shoshan-Barmatz, V. (1991) Involvement of protein phosphorylation in activation of
$Ca^{2+}$ efflux from sarcoplasmic reticulum. Biochem. J. 276, 97-102 https://doi.org/10.1042/bj2760097 - Giannini, G., Conti, A., Mammarella, S., Scrobogna, M., and Sorrentino, V. (1995) The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues. J. Cell Biol. 128, 893-904 https://doi.org/10.1083/jcb.128.5.893
- Grabner, M., Dirksen, R. T., Suda, N., and Beam, K. G. (1999) The II-III loop of the skeletal muscle dihydropyridine receptor is responsible for the Bi-directional coupling with the ryanodine receptor. J. Biol. Chem. 274, 21913-21919 https://doi.org/10.1074/jbc.274.31.21913
- Greka, A., Navarro, B., Oancea, E., Duggan, A., and Clapham, D. E. (2003) TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nat. Neurosci. 6, 837- 845 https://doi.org/10.1038/nn1092
- Grunwald, R. and Meissner, G. (1995) Lumenal sites and C terminus accessibility of the skeletal muscle calcium release channel (ryanodine receptor). J. Biol. Chem. 270, 11338-11347 https://doi.org/10.1074/jbc.270.19.11338
-
Hadad, N., Zable, A. C., Abramson, J. J., and Shoshan-Barmatz, V. (1994)
$Ca^{2+}$ binding sites of the ryanodine receptor/$Ca^{2+}$ release channel of sarcoplasmic reticulum. Low affinity binding site(s) as probed by terbium fluorescence. J. Biol. Chem. 269, 24864-24869 - Hakamata, Y., Nakai, J., Takeshima, H., and Imoto, K. (1992) Primary structure and distribution of a novel ryanodine receptor/ calcium release channel from rabbit brain. FEBS Lett. 312, 229-235 https://doi.org/10.1016/0014-5793(92)80941-9
- Harteneck, C. (2003) Proteins modulating TRP channel function. Cell Calcium 33, 303-310 https://doi.org/10.1016/S0143-4160(03)00043-5
- Hasenfuss, G., Mulieri, L. A., Leavitt, B. J., Allen, P. D., Holubarsch, C., et al. (1992) Contractile protein function in failing and nonfailing human myocardium. Basic. Res. Cardiol. 87, 107-116
- Hassock, S. R., Zhu, M. X., Trost, C., Flockerzi, V., and Authi, K. S. (2002) Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel. Blood 100, 2801-2811 https://doi.org/10.1182/blood-2002-03-0723
-
Herrmann-Frank, A. and Varsanyi, M. (1993) Enhancement of
$Ca^{2+}$ release channel activity by phosphorylation of the skeletal muscle ryanodine receptor. FEBS Lett. 332, 237-242 https://doi.org/10.1016/0014-5793(93)80640-G - Hill, A. P. and Sitsapesan, R. (2002) DIDS modifies the conductance, gating, and inactivation mechanisms of the cardiac ryanodine receptor. Biophys. J. 82, 3037-3047 https://doi.org/10.1016/S0006-3495(02)75644-0
- Hisatsune, C., Kuroda, Y., Nakamura, K., Inoue, T., Nakamura, T., et al. (2004) Regulation of TRPC6 channel activity by tyrosine phosphorylation. J. Biol. Chem. 279, 18887-18894 https://doi.org/10.1074/jbc.M311274200
- Hofmann, T., Obukhov, A. G., Schaefer, M., Harteneck, C., Gudermann, T., et al. (1999) Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature 397, 259-263 https://doi.org/10.1038/16711
- Hofmann, T., Schaefer, M., Schultz, G., and Gudermann, T. (2000a) Cloning, expression and subcellular localization of two novel splice variants of mouse transient receptor potential channel 2. Biochem. J. 351, 115-122 https://doi.org/10.1042/0264-6021:3510115
- Hofmann, T., Schaefer, M., Schultz, G., and Gudermann, T. (2000b) Transient receptor potential channels as molecular substrates of receptor-mediated cation entry. J. Mol. Med. 78, 14-25 https://doi.org/10.1007/s001090050378
- Hofmann, T., Schaefer, M., Schultz, G., and Gudermann, T. (2002) Subunit composition of mammalian transient receptor potential channels in living cells. Proc. Natl. Acad. Sci. USA 99, 7461-7466
-
Imagawa, T., Smith, J. S., Coronado, R., and Campbell, K. P. (1987) Purified ryanodine receptor from skeletal muscle sarcoplasmic reticulum is the
$Ca^{2+}$ -permeable pore of the calcium release channel. J. Biol. Chem. 262, 16636-16643 -
Inoue, R., Okada, T., Onoue, H., Hara, Y., Shimizu, S., et al. (2001) The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor- activated
$Ca^{2+}$ -permeable cation channel. Circ. Res. 88, 325-332 https://doi.org/10.1161/01.RES.88.3.325 - Inui, M., Saito, A., and Fleischer, S. (1987) Isolation of the ryanodine receptor from cardiac sarcoplasmic reticulum and identity with the feet structures. J. Biol. Chem. 262, 15637-15642
- Ito, K., Komazaki, S., Sasamoto, K., Yoshida, M., Nishi, M., et al. (2001) Deficiency of triad junction and contraction in mutant skeletal muscle lacking junctophilin type 1. J. Cell Biol. 154, 1059-1067 https://doi.org/10.1083/jcb.200105040
- Jayaraman, T., Brillantes, A. M., Timerman, A. P., Fleischer, S., Erdjument-Bromage, H., et al. (1992) FK506 binding protein associated with the calcium release channel (ryanodine receptor). J. Biol. Chem. 267, 9474-9477
- Joffe, M., Savage, N., and Silove, M. (1992) The biochemistry of malignant hyperthermia: recent concepts. Int. J. Biochem. 24, 387-398 https://doi.org/10.1016/0020-711X(92)90029-Z
- Jung, S., Strotmann, R., Schultz, G., and Plant, T. D. (2002) TRPC6 is a candidate channel involved in receptor-stimulated cation currents in A7r5 smooth muscle cells. Am. J. Physiol. Cell Physiol. 282, C347-359 https://doi.org/10.1152/ajpcell.00283.2001
- Jung, S., Muhle, A., Schaefer, M., Strotmann, R., Schultz, G., et al. (2003) Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth. J. Biol. Chem. 278, 3562-3571 https://doi.org/10.1074/jbc.M211484200
- Kausch, K., Lehmann-Horn, F., Janka, M., Wieringa, B., Grimm, T., et al. (1991) Evidence for linkage of the central core disease locus to the proximal long arm of human chromosome 19. Genomics 10, 765-769 https://doi.org/10.1016/0888-7543(91)90461-M
-
Kawasaki, T. and Kasai, M. (1989) Disulfonic stilbene derivatives open the
$Ca^{2+}$ release channel of sarcoplasmic reticulum. J. Biochem (Tokyo). 106, 401-405 https://doi.org/10.1093/oxfordjournals.jbchem.a122865 - Keating, K. E., Quane, K. A., Manning, B. M., Lehane, M., Hartung, E., et al. (1994) Detection of a novel RYR1 mutation in four malignant hyperthermia pedigrees. Hum. Mol. Genet. 3, 1855-1858 https://doi.org/10.1093/hmg/3.10.1855
- Kim, D. H. and Ikemoto, N. (1986) Involvement of 60-kilodalton phosphoprotein in the regulation of calcium release from skeletal muscle sarcoplasmic reticulum. J. Biol. Chem. 261, 11674-11679
- Kim, D. H., Ohnishi, S. T., and Ikemoto, N. (1983) Kinetic studies of calcium release from sarcoplasmic reticulum in vitro. J. Biol. Chem. 258, 9662-9668
- Kim, S. J., Kim, Y. S., Yuan, J. P., Petralia, R. S., Worley, P. F., et al. (2003) Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1. Nature 426, 285-291 https://doi.org/10.1038/nature02162
-
Kirino, Y., Osakabe, M., and Shimizu, H. (1983)
$Ca^{2+}$ -induced$Ca^{2+}$ release from fragmented sarcoplasmic reticulum:$Ca^{2+}$ - dependent passive$Ca^{2+}$ efflux. J. Biochem (Tokyo). 94, 1111-1118 https://doi.org/10.1093/oxfordjournals.jbchem.a134454 - Kiselyov, K. I., Shin, D. M., Wang, Y., Pessah, I. N., Allen, P. D., et al. (2000) Gating of store-operated channels by conformational coupling to ryanodine receptors. Mol. Cell 6, 421-431 https://doi.org/10.1016/S1097-2765(00)00041-1
- Klein, M. G., Cheng, H., Santana, L. F., Jiang, Y. H., Lederer, W. J., et al. (1996) Two mechanisms of quantized calcium release in skeletal muscle. Nature 379, 455-458 https://doi.org/10.1038/379455a0
- Kunichika, N., Landsberg, J. W., Yu, Y., Kunichika, H., Thistlethwaite, P. A., et al. (2004) Bosentan inhibits transient receptor potential channel expression in pulmonary vascular myocytes. Am. J. Respir. Crit. Care. Med. 170, 1101-1107 https://doi.org/10.1164/rccm.200312-1668OC
- Kwan, H. Y., Huang, Y., and Yao, X. (2004) Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G. Proc. Natl. Acad. Sci. USA 101, 2625-2630
- Lai, F. A., Erickson, H. P., Rousseau, E., Liu, Q. Y., and Meissner, G. (1988) Purification and reconstitution of the calcium release channel from skeletal muscle. Nature 331, 315-319 https://doi.org/10.1038/331315a0
- Laitinen, P. J., Brown, K. M., Piippo, K., Swan, H., Devaney, J. M., et al. (2001) Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia. Circulation 103, 485-490 https://doi.org/10.1161/01.CIR.103.4.485
- Lam, E., Martin, M. M., Timerman, A. P., Sabers, C., Fleischer, S., et al. (1995) A novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptor. J. Biol. Chem. 270, 26511-26522 https://doi.org/10.1074/jbc.270.44.26511
- Ledbetter, M. W., Preiner, J. K., Louis, C. F., and Mickelson, J. R. (1994) Tissue distribution of ryanodine receptor isoforms and alleles determined by reverse transcription polymerase chain reaction. J. Biol. Chem. 269, 31544-31551
- Leddy, J. J., Murphy, B. J., Qu, Y., Doucet, J. P., Pratt, C., et al. (1993) A 60 kDa polypeptide of skeletal-muscle sarcoplasmic reticulum is a calmodulin-dependent protein kinase that associates with and phosphorylates several membrane proteins. Biochem. J. 295, 849-856 https://doi.org/10.1042/bj2950849
- Lee-Kwon, W., Wade, J. B., Zhang, Z., Pallone, T. L., and Weinman, E. J. (2005) Expression of TRPC4 channel protein that interacts with NHERF-2 in rat descending vasa recta. Am. J. Physiol. Cell Physiol. 288, C942-949 https://doi.org/10.1152/ajpcell.00417.2004
- Lee, E. H., Cherednichenko, G., Pessah, I. N., and Allen, P. D. (2006) Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins. J. Biol. Chem. 281, 10042-10048 https://doi.org/10.1074/jbc.M600981200
- Lee, E. H., Lopez, J. R., Li, J., Protasi, F., Pessah, I. N., et al. (2004a) Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module. Am. J. Physiol. Cell Physiol. 286, C179-189 https://doi.org/10.1152/ajpcell.00176.2003
- Lee, E. H., Rho, S. H., Kwon, S. J., Eom, S. H., Allen, P. D., et al. (2004b) N-terminal region of FKBP12 is essential for binding to the skeletal ryanodine receptor. J. Biol. Chem. 279, 26481-26488 https://doi.org/10.1074/jbc.M309574200
- Lehnart, S. E., Huang, F., Marx, S. O., and Marks, A. R. (2003) Immunophilins and coupled gating of ryanodine receptors. Curr. Top. Med. Chem. 3, 1383-1391 https://doi.org/10.2174/1568026033451907
- Leypold, B. G., Yu, C. R., Leinders-Zufall, T., Kim, M. M., Zufall, F., et al. (2002) Altered sexual and social behaviors in trp2 mutant mice. Proc. Natl. Acad. Sci. USA 99, 6376- 6381
- Li, H. S., Xu, X. Z., and Montell, C. (1999) Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. Neuron 24, 261-273 https://doi.org/10.1016/S0896-6273(00)80838-7
- Li, S., Westwick, J., and Poll, C. (2003) Transient receptor potential (TRP) channels as potential drug targets in respiratory disease. Cell Calcium 33, 551-558 https://doi.org/10.1016/S0143-4160(03)00060-5
- Li, S., Westwick, J., Cox, B., and Poll, C. T. (2004) TRP channels as drug targets. Novartis Found. Symp. 258, 204-213
- Li, Y., Jia, Y. C., Cui, K., Li, N., Zheng, Z. Y., et al. (2005) Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature 434, 894-898 https://doi.org/10.1038/nature03477
-
Liman, E. R. (2003) Regulation by voltage and adenine nucleotides of a
$Ca^{2+}$ -activated cation channel from hamster vomeronasal sensory neurons. J. Physiol. 548, 777-787 https://doi.org/10.1113/jphysiol.2002.037119 -
Lintschinger, B., Balzer-Geldsetzer, M., Baskaran, T., Graier, W. F., Romanin, C., et al. (2000) Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and
$Ca^{2+}$ -sensitive cation channels. J. Biol. Chem. 275, 27799-27805 - Liu, Q. Y., Lai, F. A., Rousseau, E., Jones, R. V., and Meissner, G. (1989) Multiple conductance states of the purified calcium release channel complex from skeletal sarcoplasmic reticulum. Biophys. J. 55, 415-424 https://doi.org/10.1016/S0006-3495(89)82835-8
-
Liu, X., Singh, B. B., and Ambudkar, I. S. (2003) TRPC1 is required for functional store-operated
$Ca^{2+}$ channels. Role of acidic amino acid residues in the S5-S6 region. J. Biol. Chem. 278, 11337-11343 https://doi.org/10.1074/jbc.M213271200 - Liu, D., Scholze, A., Zhu, Z., Krueger, K., Thilo, F., et al. (2006) Transient receptor potential channels in essential hypertension. J. Hypertens. 24, 1115-1124 https://doi.org/10.1097/01.hjh.0000226202.80689.8f
- Lokuta, A. J., Meyers, M. B., Sander, P. R., Fishman, G. I., and Valdivia, H. H. (1997) Modulation of cardiac ryanodine receptors by sorcin. J. Biol. Chem. 272, 25333-25338 https://doi.org/10.1074/jbc.272.40.25333
- Lokuta, A. J., Rogers, T. B., Lederer, W. J., and Valdivia, H. H. (1995) Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism. J. Physiol. 487, 609-622 https://doi.org/10.1113/jphysiol.1995.sp020904
- Louvet, L. and Collin, T. (2005) Involvement of ryanodine receptors in IP3-mediated calcium signalling in neurons. A modelling approach. Neurosci. Lett. 381, 149-153 https://doi.org/10.1016/j.neulet.2005.02.024
- Lucas, P., Ukhanov, K., Leinders-Zufall, T., and Zufall, F. (2003) A diacylglycerol-gated cation channel in vomeronasal neuron dendrites is impaired in TRPC2 mutant mice: mechanism of pheromone transduction. Neuron 40, 551-561 https://doi.org/10.1016/S0896-6273(03)00675-5
- Lussier, M. P., Cayouette, S., Lepage, P. K., Bernier, C. L., Francoeur, N., et al. (2005) MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC. J. Biol. Chem. 280, 19393-19400 https://doi.org/10.1074/jbc.M500391200
- Ma, J. (1993) Block by ruthenium red of the ryanodine-activated calcium release channel of skeletal muscle. J. Gen. Physiol. 102, 1031-1056 https://doi.org/10.1085/jgp.102.6.1031
- Ma, J., Fill, M., Knudson, C. M., Campbell, K. P., and Coronado, R. (1988) Ryanodine receptor of skeletal muscle is a gap junction-type channel. Science 242, 99-102 https://doi.org/10.1126/science.2459777
-
Ma, H. T., Patterson, R. L., van Rossum, D. B., Birnbaumer, L., Mikoshiba, K., et al. (2000) Requirement of the inositol trisphosphate receptor for activation of store-operated
$Ca^{2+}$ channels. Science 287, 1647-1651 https://doi.org/10.1126/science.287.5458.1647 - Ma, H. T., Venkatachalam, K., Parys, J. B., and Gill, D. L. (2002) Modification of store-operated channel coupling and inositol trisphosphate receptor function by 2-aminoethoxydi-phenyl borate in DT40 lymphocytes. J. Biol. Chem. 277, 6915-6922 https://doi.org/10.1074/jbc.M107755200
- MacLennan, D. H. and Phillips, M. S. (1992) Malignant hyperthermia. Science 256, 789-794 https://doi.org/10.1126/science.1589759
- Maroto, R., Raso, A., Wood, T. G., Kurosky, A., Martinac, B., et al. (2005) TRPC1 forms the stretch-activated cation channel in vertebrate cells. Nat. Cell Biol. 7, 179-185 https://doi.org/10.1038/ncb1218
- Maruyama, Y., Nakanishi, Y., Walsh, E. J., Wilson, D. P., Welsh, D. G., et al. (2006) Heteromultimeric TRPC6-TRPC7 channels contribute to arginine vasopressin-induced cation current of A7r5 vascular smooth muscle cells. Circ. Res. 9 (in press)
- Marx, S. O., Reiken, S., Hisamatsu, Y., Jayaraman, T., Burkhoff, D., et al. (2000) PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101, 365-376 https://doi.org/10.1016/S0092-8674(00)80847-8
- Mayrleitner, M., Timerman, A. P., Wiederrecht, G., and Fleischer, S. (1994) The calcium release channel of sarcoplasmic reticulum is modulated by FK-506 binding protein: effect of FKBP- 12 on single channel activity of the skeletal muscle ryanodine receptor. Cell Calcium 15, 99-108 https://doi.org/10.1016/0143-4160(94)90048-5
-
Meissner, G. (1984) Adenine nucleotide stimulation of
$Ca^{2+}$ - induced$Ca^{2+}$ release in sarcoplasmic reticulum. J. Biol. Chem. 259, 2365-2374 - Meissner, G. (1986) Evidence of a role for calmodulin in the regulation of calcium release from skeletal muscle sarcoplasmic reticulum. Biochemistry 25, 244-251 https://doi.org/10.1021/bi00349a034
-
Meissner, G. (1994) Ryanodine receptor/
$Ca^{2+}$ release channels and their regulation by endogenous effectors. Annu. Rev. Physiol. 56, 485-508 https://doi.org/10.1146/annurev.ph.56.030194.002413 -
Meissner, G. and Henderson, J. S. (1987) Rapid calcium release from cardiac sarcoplasmic reticulum vesicles is dependent on
$Ca^{2+}$ and is modulated by$Mg^{2+}$ , adenine nucleotide, and calmodulin. J. Biol. Chem. 262, 3065-3073 - Montell, C. (2005) The TRP superfamily of cation channels. Sci. STKE 2005, re3
- Montell, C., Birnbaumer, L., and Flockerzi, V. (2002) The TRP channels, a remarkably functional family. Cell 108, 595-598 https://doi.org/10.1016/S0092-8674(02)00670-0
- Morales-Tlalpan, V., Arellano, R. O., and Diaz-Munoz, M. (2005) Interplay between ryanodine and IP3 receptors in ATPstimulated mouse luteinized-granulosa cells. Cell Calcium 37, 203-213 https://doi.org/10.1016/j.ceca.2004.10.001
-
Mori, Y., Wakamori, M., Miyakawa, T., Hermosura, M., Hara, Y., et al. (2002) Transient receptor potential 1 regulates capacitative
$Ca^{2+}$ entry and$Ca^{2+}$ release from endoplasmic reticulum in B lymphocytes. J. Exp. Med. 195, 673-681 https://doi.org/10.1084/jem.20011758 -
Moutin, M. J. and Dupont, Y. (1988) Rapid filtration studies of
$Ca^{2+}$ -induced$Ca^{2+}$ release from skeletal sarcoplasmic reticulum. Role of monovalent ions. J. Biol. Chem. 263, 4228- 4235 - Mulley, J. C., Kozman, H. M., Phillips, H. A., Gedeon, A. K., McCure, J. A., et al. (1993) Refined genetic localization for central core disease. Am. J. Hum. Genet. 52, 398-405
- Munsch, T., Freichel, M., Flockerzi, V., and Pape, H. C. (2003) Contribution of transient receptor potential channels to the control of GABA release from dendrites. Proc. Natl. Acad. Sci. USA 100, 16065-16070
- Nagasaki, K. and Kasai, M. (1983) Fast release of calcium from sarcoplasmic reticulum vesicles monitored by chlortetracycline fluorescence. J. Biochem. (Tokyo) 94, 1101-1109 https://doi.org/10.1093/oxfordjournals.jbchem.a134453
- Nakai, J., Imagawa, T., Hakamat, Y., Shigekawa, M., Takeshima, H., et al. (1990) Primary structure and functional expression from cDNA of the cardiac ryanodine receptor/ calcium release channel. FEBS Lett. 271, 169-177 https://doi.org/10.1016/0014-5793(90)80399-4
- Nakai, J., Dirksen, R. T., Nguyen, H. T., Pessah, I. N., Beam, K. G., et al. (1996) Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor. Nature 380, 72-75 https://doi.org/10.1038/380072a0
-
Nilius, B. (2004) Store-operated
$Ca^{2+}$ entry channels: still elusive! Sci. STKE 2004, pe36 - Nilius, B., Voets, T., and Peters, J. (2005) TRP channels in disease. Sci. STKE 2005, re8
- Nishi, M., Mizushima, A., Nakagawara, K., and Takeshima, H. (2000) Characterization of human junctophilin subtype genes. Biochem. Biophys. Res. Commun. 273, 920-927 https://doi.org/10.1006/bbrc.2000.3011
-
Nishida, M., Sugimoto, K., Hara, Y., Mori, E., Morii, T., et al. (2003) Amplification of receptor signalling by
$Ca^{2+}$ entrymediated translocation and activation of PLCgamma2 in B lymphocytes. EMBO J. 22, 4677-4688 https://doi.org/10.1093/emboj/cdg457 - Obukhov, A. G. and Nowycky, M. C. (2004) TRPC5 activation kinetics are modulated by the scaffolding protein ezrin/ radixin/moesin-binding phosphoprotein-50 (EBP50). J. Cell. Physiol. 201, 227-235 https://doi.org/10.1002/jcp.20057
-
Okada, T., Inoue, R., Yamazaki, K., Maeda, A., Kurosaki, T., et al. (1999) Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7.
$Ca^{2+}$ -permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor. J. Biol. Chem. 274, 27359-27370 https://doi.org/10.1074/jbc.274.39.27359 -
Okada, T., Shimizu, S., Wakamori, M., Maeda, A., Kurosaki, T., et al. (1998) Molecular cloning and functional characterization of a novel receptor-activated TRP
$Ca^{2+}$ channel from mouse brain. J. Biol. Chem. 273, 10279-10287 https://doi.org/10.1074/jbc.273.17.10279 - Orlova, E. V., Serysheva, I. I., van Heel, M., Hamilton, S. L., and Chiu, W. (1996) Two structural configurations of the skeletal muscle calcium release channel. Nat. Struct. Biol. 3, 547-552 https://doi.org/10.1038/nsb0696-547
-
Otsu, K., Willard, H. F., Khanna, V. K., Zorzato, F., Green, N. M., et al. (1990) Molecular cloning of cDNA encoding the
$Ca^{2+}$ release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum. J. Biol. Chem. 265, 13472-13483 - Ottini, L., Marziali, G., Conti, A., Charlesworth, A., and Sorrentino, V. (1996) Alpha and beta isoforms of ryanodine receptor from chicken skeletal muscle are the homologues of mammalian RyR1 and RyR3. Biochem. J. 315, 207-216 https://doi.org/10.1042/bj3150315
- Oyamada, H., Murayama, T., Takagi, T., Iino, M., Iwabe, N., et al. (1994) Primary structure and distribution of ryanodine-binding protein isoforms of the bullfrog skeletal muscle. J. Biol. Chem. 269, 17206-17214
- Pan, Z., Yang, D., Nagaraj, R. Y., Nosek, T. A., Nishi, M., et al. (2002) Dysfunction of store-operated calcium channel in muscle cells lacking mg29. Nat. Cell Biol. 4, 379-383 https://doi.org/10.1038/ncb788
- Pape, H. C., Munsch, T., and Budde, T. (2004) Novel vistas of calcium-mediated signalling in the thalamus. Pflugers Arch. 448, 131-138 https://doi.org/10.1007/s00424-003-1234-5
-
Paria, B. C., Vogel, S. M., Ahmmed, G. U., Alamgir, S., Shroff, J., et al. (2004) Tumor necrosis factor-alpha-induced TRPC1 expression amplifies store-operated
$Ca^{2+}$ influx and endothelial permeability. Am. J. Physiol. Lung Cell. Mol. Physiol. 287, L1303-1313 https://doi.org/10.1152/ajplung.00240.2004 -
Patel, J. R., Coronado, R., and Moss, R. L. (1995) Cardiac sarcoplasmic reticulum phosphorylationincreases
$Ca^{2+}$ release induced by flash photolysis of nitr-5. Circ. Res. 77, 943-949 https://doi.org/10.1161/01.RES.77.5.943 -
Payne, A. M., Zheng, Z., Gonzalez, E., Wang, Z. M., Messi, M. L., et al. (2004) External
$Ca^{2+}$ -dependent excitationcontraction coupling in a population of ageing mouse skeletal muscle fibres. J. Physiol. 560, 137-155 https://doi.org/10.1113/jphysiol.2004.067322 - Pedersen, S. F., Owsianik, G., and Nilius, B. (2005) TRP channels: an overview. Cell Calcium 38, 233-252 https://doi.org/10.1016/j.ceca.2005.06.028
- Pessah, I. N., Waterhouse, A. L., and Casida, J. E. (1985) The calcium-ryanodine receptor complex of skeletal and cardiac muscle. Biochem. Biophys. Res. Commun. 128, 449-456 https://doi.org/10.1016/0006-291X(85)91699-7
- Philipp, S., Strauss, B., Hirnet, D., Wissenbach, U., Mery, L., et al. (2003) TRPC3 mediates T-cell receptor-dependent calcium entry in human T-lymphocytes. J. Biol. Chem. 278, 26629-26638 https://doi.org/10.1074/jbc.M304044200
- Pieske, B., Kretschmann, B., Meyer, M., Holubarsch, C., Weirich, J., et al. (1995) Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy. Circulation 92, 1169-1178 https://doi.org/10.1161/01.CIR.92.5.1169
- Plank, B., Wyskovsky, W., Hohenegger, M., Hellmann, G., and Suko, J. (1988) Inhibition of calcium release from skeletal muscle sarcoplasmic reticulum by calmodulin. Biochim. Biophys. Acta 938, 79-88 https://doi.org/10.1016/0005-2736(88)90124-1
-
Plant, T. D. and Schaefer, M. (2003) TRPC4 and TRPC5: receptor- operated
$Ca^{2+}$ -permeable nonselective cation channels. Cell Calcium 33, 441-450 https://doi.org/10.1016/S0143-4160(03)00055-1 - Priori, S. G., Napolitano, C., Tiso, N., Memmi, M., Vignati, G., et al. (2001) Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia. Circulation 103, 196-200 https://doi.org/10.1161/01.CIR.103.2.196
- Protasi, F., Franzini-Armstrong, C., and Allen, P. D. (1998) Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle. J. Cell Biol. 140, 831-842 https://doi.org/10.1083/jcb.140.4.831
- Protasi, F., Takekura, H., Wang, Y., Chen, S. R., Meissner, G., et al. (2000) RYR1 and RYR3 have different roles in the assembly of calcium release units of skeletal muscle. Biophys. J. 79, 2494-2508 https://doi.org/10.1016/S0006-3495(00)76491-5
- Protasi, F., Paolini, C., Nakai, J., Beam, K. G., Franzini- Armstrong, C., et al. (2002) Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle. Biophys. J. 83, 3230-3244 https://doi.org/10.1016/S0006-3495(02)75325-3
- Quane, K. A., Healy, J. M., Keating, K. E., Manning, B. M., Couch, F. J., et al. (1993) Mutations in the ryanodine receptor gene in central core disease and malignant hyperthermia. Nat. Genet. 5, 51-55 https://doi.org/10.1038/ng0993-51
- Quane, K. A., Keating, K. E., Healy, J. M., Manning, B. M., Krivosic-Horber, R., et al. (1994) Mutation screening of the RYR1 gene in malignant hyperthermia: detection of a novel Tyr to Ser mutation in a pedigree with associated central cores. Genomics 23, 236-239 https://doi.org/10.1006/geno.1994.1483
- Ramsey, I. S., Delling, M., and Clapham, D. E. (2006) An introduction to TRP channels. Annu. Rev. Physiol. 68, 619-647 https://doi.org/10.1146/annurev.physiol.68.040204.100431
- Reading, S. A., Earley, S., Waldron, B. J., Welsh, D. G., and Brayden, J. E. (2005) TRPC3 mediates pyrimidine receptorinduced depolarization of cerebral arteries. Am. J. Physiol. Heart. Circ. Physiol. 288, H2055-2061 https://doi.org/10.1152/ajpheart.00861.2004
- Reiser, J., Polu, K. R., Moller, C. C., Kenlan, P., Altintas, M. M., et al. (2005) TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat. Genet. 37, 739-744 https://doi.org/10.1038/ng1592
- Rios, E. and Pizarro, G. (1991) Voltage sensor of excitationcontraction coupling in skeletal muscle. Physiol. Rev. 71, 849-908 https://doi.org/10.1152/physrev.1991.71.3.849
-
Rosker, C., Graziani, A., Lukas, M., Eder, P., Zhu, M. X., et al. (2004)
$Ca^{2+}$ signaling by TRPC3 involves$Na^+$ entry and local coupling to the$Na^+$ /$Ca^{2+}$ exchanger. J. Biol. Chem. 279, 13696-13704 https://doi.org/10.1074/jbc.M308108200 -
Rousseau, E., Smith, J. S., Henderson, J. S., and Meissner, G. (1986) Single channel and 45
$Ca^{2+}$ flux measurements of the cardiac sarcoplasmic reticulum calcium channel. Biophys. J. 50, 1009-1014 https://doi.org/10.1016/S0006-3495(86)83543-3 - Saimi, Y. and Kung, C. (2002) Calmodulin as an ion channel subunit. Annu. Rev. Physiol. 64, 289-311 https://doi.org/10.1146/annurev.physiol.64.100301.111649
- Sampieri, A., Diaz-Munoz, M., Antaramian, A., and Vaca, L. (2005) The foot structure from the type 1 ryanodine receptor is required for functional coupling to store-operated channels. J. Biol. Chem. 280, 24804-24815 https://doi.org/10.1074/jbc.M501487200
- Samso, M., Wagenknecht, T., and Allen, P. D. (2005) Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM. Nat. Struct. Mol. Biol. 12, 539-544 https://doi.org/10.1038/nsmb938
- Sandow, A. (1965) Excitation-contraction coupling in skeletal muscle. Pharmacol. Rev. 17, 265-320
- Schaefer, M., Plant, T. D., Obukhov, A. G., Hofmann, T., Gudermann, T., et al. (2000) Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5. J. Biol. Chem. 275, 17517-17526 https://doi.org/10.1074/jbc.275.23.17517
- Schneider, M. F. (1994) Control of calcium release in functioning skeletal muscle fibers. Annu. Rev. Physiol. 56, 463-484 https://doi.org/10.1146/annurev.ph.56.030194.002335
-
Seifert, J. and Casida, J. E. (1986)
$Ca^{2+}$ -dependent ryanodine binding site: soluble preparation from rabbit cardiac sarcoplasmic reticulum. Biochim. Biophys. Acta 861, 399-405 https://doi.org/10.1016/0005-2736(86)90447-5 -
Seiler, S., Wegener, A. D., Whang, D. D., Hathaway, D. R., and Jones, L. R. (1984) High molecular weight proteins in cardiac and skeletal muscle junctional sarcoplasmic reticulum vesicles bind calmodulin, are phosphorylated, and are degraded by
$Ca^{2+}$ -activated protease. J. Biol. Chem. 259, 8550-8557 - Sewell, T. J., Lam, E., Martin, M. M., Leszyk, J., Weidner, J., et al. (1994) Inhibition of calcineurin by a novel FK-506-binding protein. J. Biol. Chem. 269, 21094-21102
-
Sham, J. S., Cleemann, L., and Morad, M. (1995) Functional coupling of
$Ca^{2+}$ channels and ryanodine receptors in cardiac myocytes. Proc. Natl. Acad. Sci. USA 92, 121-125 - Shenolikar, S., Voltz, J. W., Cunningham, R., and Weinman, E. J. (2004) Regulation of ion transport by the NHERF family of PDZ proteins. Physiology (Bethesda) 19, 362-369 https://doi.org/10.1152/physiol.00020.2004
- Shi, J., Mori, E., Mori, Y., Mori, M., Li, J., et al. (2004) Multiple regulation by calcium of murine homologues of transient receptor potential proteins TRPC6 and TRPC7 expressed in HEK293 cells. J. Physiol. 561, 415-432 https://doi.org/10.1113/jphysiol.2004.075051
- Shim, S., Goh, E. L., Ge, S., Sailor, K., Yuan, J. P., et al. (2005) XTRPC1-dependent chemotropic guidance of neuronal growth cones. Nat. Neurosci. 8, 730-735 https://doi.org/10.1038/nn1459
- Sitsapesan, R. (1999) Similarities in the effects of DIDS, DBDS and suramin on cardiac ryanodine receptor function. J. Membr. Biol. 168, 159-168 https://doi.org/10.1007/s002329900506
-
Smith, J. S., Coronado, R., and Meissner, G. (1986) Single channel measurements of the calcium release channel from skeletal muscle sarcoplasmic reticulum. Activation by
$Ca^{2+}$ and ATP and modulation by$Mg^{2+}$ . J. Gen. Physiol. 88, 573-588 https://doi.org/10.1085/jgp.88.5.573 - Smith, J. S., Imagawa, T., Ma, J., Fill, M., Campbell, K. P., et al. (1988) Purified ryanodine receptor from rabbit skeletal muscle is the calcium-release channel of sarcoplasmic reticulum. J. Gen. Physiol. 92, 1-26 https://doi.org/10.1085/jgp.92.1.1
- Stange, M., Xu, L., Balshaw, D., Yamaguchi, N., and Meissner, G. (2003) Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants. J. Biol. Chem. 278, 51693-51702 https://doi.org/10.1074/jbc.M310406200
- Stowers, L., Holy, T. E., Meister, M., Dulac, C., and Koentges, G. (2002) Loss of sex discrimination and male-male aggression in mice deficient for TRP2. Science 295, 1493-1500 https://doi.org/10.1126/science.1069259
- Strubing, C., Krapivinsky, G., Krapivinsky, L., and Clapham, D. E. (2001) TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Neuron 29, 645-655 https://doi.org/10.1016/S0896-6273(01)00240-9
- Strubing, C., Krapivinsky, G., Krapivinsky, L., and Clapham, D. E. (2003) Formation of novel TRPC channels by complex subunit interactions in embryonic brain. J. Biol. Chem. 278, 39014-39019 https://doi.org/10.1074/jbc.M306705200
- Suko, J., Maurer-Fogy, I., Plank, B., Bertel, O., Wyskovsky, W., et al. (1993) Phosphorylation of serine 2843 in ryanodine receptor- calcium release channel of skeletal muscle by cAMP-, cGMP- and CaM-dependent protein kinase. Biochim. Biophys. Acta 1175, 193-206 https://doi.org/10.1016/0167-4889(93)90023-I
-
Sumbilla, C. and Inesi, G. (1987) Rapid filtration measurements of
$Ca^{2+}$ release from cisternal sarcoplasmic reticulum vesicles. FEBS Lett. 210, 31-36 https://doi.org/10.1016/0014-5793(87)81292-9 -
Sutko, J. L. and Airey, J. A. (1996) Ryanodine receptor
$Ca^{2+}$ release channels: does diversity in form equal diversity in function? Physiol. Rev. 76, 1027-1071 https://doi.org/10.1152/physrev.1996.76.4.1027 - Sutton, K. A., Jungnickel, M. K., Wang, Y., Cullen, K., Lambert, S., et al. (2004) Enkurin is a novel calmodulin and TRPC channel binding protein in sperm. Dev. Biol. 274, 426-435 https://doi.org/10.1016/j.ydbio.2004.07.031
-
Sweeney, M., McDaniel, S. S., Platoshyn, O., Zhang, S., Yu, Y., et al. (2002a) Role of capacitative
$Ca^{2+}$ entry in bronchial contraction and remodeling. J. Appl. Physiol. 92, 1594-1602 https://doi.org/10.1152/japplphysiol.00722.2001 -
Sweeney, M., Yu, Y., Platoshyn, O., Zhang, S., McDaniel, S. S., et al. (2002b) Inhibition of endogenous TRP1 decreases capacitative
$Ca^{2+}$ entry and attenuates pulmonary artery smooth muscle cell proliferation. Am. J. Physiol. Lung Cell. Mol. Physiol. 283, L144-155 - Takasago, T., Imagawa, T., Furukawa, K., Ogurusu, T., and Shigekawa, M. (1991) Regulation of the cardiac ryanodine receptor by protein kinase-dependent phosphorylation. J. Biochem(Tokyo). 109, 163-170
- Takeshima, H., Nishimura, S., Matsumoto, T., Ishida, H., Kangawa, K., et al. (1989) Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor. Nature 339, 439-445 https://doi.org/10.1038/339439a0
- Takeshima, H., Iino, M., Takekura, H., Nishi, M., Kuno, J., et al. (1994) Excitation-contraction uncoupling and muscular degeneration in mice lacking functional skeletal muscle ryanodinereceptor gene. Nature 369, 556-559 https://doi.org/10.1038/369556a0
- Takeshima, H., Komazaki, S., Nishi, M., Iino, M., and Kangawa, K. (2000) Junctophilins: a novel family of junctional membrane complex proteins. Mol. Cell 6, 11-22 https://doi.org/10.1016/S1097-2765(00)00003-4
- Tang, Y., Tang, J., Chen, Z., Trost, C., Flockerzi, V., et al. (2000) Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF. J. Biol. Chem. 275, 37559-37564 https://doi.org/10.1074/jbc.M006635200
- Timerman, A. P., Ogunbumni, E., Freund, E., Wiederrecht, G., Marks, A. R., et al. (1993) The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein. Dissociation and reconstitution of FKBP-12 to the calcium release channel of skeletal muscle sarcoplasmic reticulum. J. Biol. Chem. 268, 22992-22999
- Timerman, A. P., Jayaraman, T., Wiederrecht, G., Onoue, H., Marks, A. R., et al. (1994) The ryanodine receptor from canine heart sarcoplasmic reticulum is associated with a novel FK-506 binding protein. Biochem. Biophys. Res. Commun. 198, 701-706 https://doi.org/10.1006/bbrc.1994.1101
-
Tiruppathi, C., Freichel, M., Vogel, S. M., Paria, B. C., Mehta, D., et al. (2002) Impairment of store-operated
$Ca^{2+}$ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability. Circ. Res. 91, 70-76 https://doi.org/10.1161/01.RES.0000023391.40106.A8 - Tiso, N., Stephan, D. A., Nava, A., Bagattin, A., Devaney, J. M., et al. (2001) Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2). Hum. Mol. Genet. 10, 189-194 https://doi.org/10.1093/hmg/10.3.189
-
Tong, J., Oyamada, H., Demaurex, N., Grinstein, S., McCarthy, T. V., et al. (1997) Caffeine and halothane sensitivity of intracellular
$Ca^{2+}$ release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hyperthermia and/or central core disease. J. Biol. Chem. 272, 26332-26339 https://doi.org/10.1074/jbc.272.42.26332 - Trebak, M., Bird, G. S., McKay, R. R., and Putney, J. W., Jr. (2002) Comparison of human TRPC3 channels in receptoractivated and store-operated modes. Differential sensitivity to channel blockers suggests fundamental differences in channel composition. J. Biol. Chem. 277, 21617-21623 https://doi.org/10.1074/jbc.M202549200
-
Valdivia, H. H., Kaplan, J. H., Ellis-Davies, G. C., and Lederer, W. J. (1995) Rapid adaptation of cardiac ryanodine receptors: modulation by
$Mg^{2+}$ and phosphorylation. Science 267, 1997-2000 https://doi.org/10.1126/science.7701323 - Vandebrouck, C., Martin, D., Colson-Van Schoor, M., Debaix, H., and Gailly, P. (2002) Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers. J. Cell Biol. 158, 1089-1096 https://doi.org/10.1083/jcb.200203091
-
Vannier, B., Peyton, M., Boulay, G., Brown, D., Qin, N., et al. (1999) Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative
$Ca^{2+}$ entry channel. Proc. Natl. Acad. Sci. USA 96, 2060-2064 - Vazquez, G., Wedel, B. J., Kawasaki, B. T., Bird, G. S., and Putney, J. W., Jr. (2004) Obligatory role of Src kinase in the signaling mechanism for TRPC3 cation channels. J. Biol. Chem. 279, 40521-40528 https://doi.org/10.1074/jbc.M405280200
- Venkatachalam, K., van Rossum, D. B., Patterson, R. L., Ma, H. T., and Gill, D. L. (2002) The cellular and molecular basis of store-operated calcium entry. Nat. Cell Biol. 4, E263-272 https://doi.org/10.1038/ncb1102-e263
- Venkatachalam, K., Zheng, F., and Gill, D. L. (2003) Regulation of canonical transient receptor potential (TRPC) channel function by diacylglycerol and protein kinase C. J. Biol. Chem. 278, 29031-29040 https://doi.org/10.1074/jbc.M302751200
- Wagenknecht, T., Carazo, J. M., Radermacher, M., and Frank, J. (1989) Three-dimensional reconstruction of the ribosome from Escherichia coli. Biophys. J. 55, 455-464 https://doi.org/10.1016/S0006-3495(89)82839-5
- Wang, J. and Best, P. M. (1992) Inactivation of the sarcoplasmic reticulum calcium channel by protein kinase. Nature 359, 739-741 https://doi.org/10.1038/359739a0
- Wang, G. X. and Poo, M. M. (2005) Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones. Nature 434, 898-904 https://doi.org/10.1038/nature03478
-
Ward, C. W., Protasi, F., Castillo, D., Wang, Y., Chen, S. R., et al. (2001) Type 1 and type 3 ryanodine receptors generate different
$Ca^{2+}$ release event activity in both intact and permeabilized myotubes. Biophys. J. 81, 3216-3230 https://doi.org/10.1016/S0006-3495(01)75957-7 -
Ward, C. W., Feng, W., Tu, J., Pessah, I. N., Worley, P. K., et al. (2004) Homer protein increases activation of
$Ca^{2+}$ sparks in permeabilized skeletal muscle. J. Biol. Chem. 279, 5781-5787 https://doi.org/10.1074/jbc.M311422200 - Wedel, B. J., Vazquez, G., McKay, R. R., St, J. Bird, G., and Putney, J. W., Jr. (2003) A calmodulin/inositol 1,4,5-trisphosphate (IP3) receptor-binding region targets TRPC3 to the plasma membrane in a calmodulin/IP3 receptor-independent process. J. Biol. Chem. 278, 25758-25765 https://doi.org/10.1074/jbc.M303890200
- Wehrens, X. H., Lehnart, S. E., Huang, F., Vest, J. A., Reiken, S. R., et al. (2003) FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise- induced sudden cardiac death. Cell 113, 829-840 https://doi.org/10.1016/S0092-8674(03)00434-3
- Welsh, D. G. and Brayden, J. E. (2001) Mechanisms of coronary artery depolarization by uridine triphosphate. Am. J. Physiol. Heart Circ. Physiol. 280, H2545-2553
- Welsh, D. G., Morielli, A. D., Nelson, M. T., and Brayden, J. E. (2002) Transient receptor potential channels regulate myogenic tone of resistance arteries. Circ. Res. 90, 248-250 https://doi.org/10.1161/hh0302.105662
- Winn, M. P., Conlon, P. J., Lynn, K. L., Farrington, M. K., Creazzo, T., et al. (2005) A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science 308, 1801-1804 https://doi.org/10.1126/science.1106215
- Witcher, D. R., Kovacs, R. J., Schulman, H., Cefali, D. C., and Jones, L. R. (1991) Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity. J. Biol. Chem. 266, 11144-11152
-
Xiao, B., Sutherland, C., Walsh, M. P., and Chen, S. R. (2004) Protein kinase A phosphorylation at serine-2808 of the cardiac
$Ca^{2+}$ -release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6). Circ. Res. 94, 487-495 https://doi.org/10.1161/01.RES.0000115945.89741.22 - Xiao, B., Zhong, G., Obayashi, M., Yang, D., Chen, K., et al. (2006) Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts. Biochem. J. 396, 7-16 https://doi.org/10.1042/BJ20060116
-
Xu, S. Z. and Beech, D. J. (2001) TrpC1 is a membrane-spanning subunit of store-operated
$Ca^{2+}$ channels in native vascular smooth muscle cells. Circ. Res. 88, 84-87 https://doi.org/10.1161/hh1201.093511 - Yano, M., el-Hayek, R., and Ikemoto, N. (1995) Role of calcium feedback in excitation-contraction coupling in isolated triads. J. Biol. Chem. 270, 19936-19942 https://doi.org/10.1074/jbc.270.34.19936
- Yu, Y., Fantozzi, I., Remillard, C. V., Landsberg, J. W., Kunichika, N., et al. (2004) Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension. Proc. Natl. Acad. Sci. USA 101, 13861-13866
- Yuan, J. P., Kiselyov, K., Shin, D. M., Chen, J., Shcheynikov, N., et al. (2003) Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell 114, 777-789 https://doi.org/10.1016/S0092-8674(03)00716-5
- Zeng, F., Xu, S. Z., Jackson, P. K., McHugh, D., Kumar, B., et al. (2004) Human TRPC5 channel activated by a multiplicity of signals in a single cell. J. Physiol. 559, 739-750 https://doi.org/10.1113/jphysiol.2004.065391
- Zhang, Z., Tang, J., Tikunova, S., Johnson, J. D., Chen, Z., et al. (2001) Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain. Proc. Natl. Acad. Sci. USA 98, 3168-3173
-
Zhu, X., Jiang, M., Peyton, M., Boulay, G., Hurst, R., et al. (1996) trp, a novel mammalian gene family essential for agonist- activated capacitative
$Ca^{2+}$ entry. Cell 85, 661-671 https://doi.org/10.1016/S0092-8674(00)81233-7 - Zimanyi, I. and Pessah, I. N. (1991) Pharmacological characterization of the specific binding of [3H]ryanodine to rat brain microsomal membranes. Brain Res. 561, 181-191 https://doi.org/10.1016/0006-8993(91)91594-Q
-
Zitt, C., Zobel, A., Obukhov, A. G., Harteneck, C., Kalkbrenner, F., et al. (1996) Cloning and functional expression of a human
$Ca^{2+}$ -permeable cation channel activated by calcium store depletion. Neuron 16, 1189-1196 https://doi.org/10.1016/S0896-6273(00)80145-2 -
Zorzato, F., Fujii, J., Otsu, K., Phillips, M., Green, N. M., et al. (1990) Molecular cloning of cDNA encoding human and rabbit forms of the
$Ca^{2+}$ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum. J. Biol. Chem. 265, 2244-2256 -
Zucchi, R. and Ronca-Testoni, S. (1997) The sarcoplasmic reticulum
$Ca^{2+}$ channel/ryanodine receptor: modulation by endogenous effectors, drugs and disease states. Pharmacol. Rev. 49, 1-51