Journal of Trauma and Injury

The Korean Society of Traumatology (대한외상학회)
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Characterization of Peroxiredoxins in the Gray matter in the spinal cord after Acute Immobilization Stress

급성 부동 스트레스 후 척수 회색질에서 Peroxiredoxin I 및 III의 발현 변화

  • Paek, Nam-Hyun (Department of Surgery, SUN General Hospital) ;
  • Kwak, Seung-Soo (Department of Surgery, SUN General Hospital) ;
  • Lee, Dong-Seok (College of animal resource science sciences, Kangwon National University) ;
  • Lee, Young-Ho (Department of anatomy, College of Medicine, Chungnam National University)
  • 백남현 (대전선병원 외과학교실) ;
  • 곽승수 (대전선병원 외과학교실) ;
  • 이동석 (강원대학교 동물생명과학부 동물 생명공학과) ;
  • 이영호 (충남대학교 의과대학 해부학실)
  • Received : 2006.09.13
  • Accepted : 2006.10.31
  • Published : 2006.12.30
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Abstract

Purpose: Many stresses produce reactive oxygen species and bring about mechanism of antioxidant reaction. Cytokine and a neurotransmitter through the cell membrane, as well as signal transduction through the cell membrane, are used for various pathological condition of the brain, such as neurodegenerative disease. There are several antioxidant enzymes in cells (superoxcide dismutase, glutathion peroxidasae, peroxiredoxin catalase, etc.) Methods: This study used single- or double-label immunohistochemical techniques to analyze mouse spinal neuron cells expressing Prx I and Prx III after acute mobilization stress. Results: Prx I was observed in dendritic cell of the gray matter of the spinal cord, and Prx III was observed in the cytoplasm of the GM of the spinal cord. Conclusion: The results of this study will help to explain differences of expression in the distributions of the peroxiredoxin enzymes of the spinal cord.

Keywords

References

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