Journal of the Speleological Society of Korea (동굴)

The Speleological Society (한국동굴학회)
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Process Optimization of Biphenile Chloromethylation

  • Pak, V.V. (Institute of Plant Substance Chemistry, Uzbekistan Academy of Sciences) ;
  • Karimov, R.K. (Institute of Plant Substance Chemistry, Uzbekistan Academy of Sciences) ;
  • Shakhidoyatov, Kh.M. (Institute of Plant Substance Chemistry, Uzbekistan Academy of Sciences) ;
  • Soh, D.W. (Myongji University)
  • Published : 2006.08.31
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Abstract

Optimization of the biphenile chloromethylation process with paraphormaldegide has been done in the presence of $ZnCl_2$ with HCl gas by the Box-Wilson method of mathematical planning of experiment. The 4,4'-(dichloromethyl)-biphenile yield dependence on the piphenile -paraphormaldegide ratio, temperature and reaction duration has been studied. A mathematical model of the process has been developed and optimal conditions for the biphenile chloromethylation procedure has been determined.

Keywords

References

  1. A.I. Belenkiy, Yu.B. Volkenshtein, N.B. Karmanov. New data on chloromethylation reaction for aromatic and geterocyclic compound. - Uspehi Himii, 1977, Vol. 46, No 9, P. 1699-1719 [Russian]
  2. USA Patent, CI. 260-240 CA, (C 07 D 263/56), No 3926964, Dec 16, 1975. Appl. July 30, 1973, No 383737
  3. Swiss Patent, Cl. C 07 B 27/00, C 08K 5/00, No 583668, Jan 14, 1977. Appl. Jun 30, 1972, No 9853/72
  4. A.G. Emelyanov. Optical bleaches and their application in textile industry. Moscow, 1971
  5. U.S. U.S. 5,326,491 (G. 252-95; C11D7/34), 05 Jul 1994, CH Appl 89/1,629, 28 Apr 1989; 9p
  6. B. Tarasyuk, W. Podkoscienly, W. Majewski. -Angew Mokromol. Chem. 1997, 251, 13-21 [Eng] https://doi.org/10.1002/apmc.1997.052510102
  7. Swiss Patent, Cl. C 07C 15/12, C 07C 143/38, No 55481, Oct 15, 1974. Appl. Aug 20, 1968
  8. Jpn, Kokai Tokkyo Koho Jp 1077, 238 [9877, 238] (Cl. C 07C22/04), Mar 24, Appl 96/233, 792, Sep 4 1996; 9 pp (Japan)
  9. V.V. Pak, R.K. Karimov, Kh.M. Shakhidoyatov. Chemistry of natural compounds, Special issue. 1999. P. 101-102
  10. S.L. Akhnazarov, V.V. Kafarov. Optimization of experiment in chemistry and chemical technology. Moscow: Visshaya Shkola. 1978. P. 158-178