Childhood Kidney Diseases
- Volume 10 Issue 2
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- Pages.238-243
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- 2006
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- 2384-0242(pISSN)
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- 2384-0250(eISSN)
A Case of Extensive Cerebral Venous Thrombosis in Childhood Nephrotic Syndrome
신증후군 환아에서 발생한 광범위한 뇌정맥 혈전증 1례
- Son, Chang-Hee (Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center) ;
- Lee, Eun-Hye (Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center) ;
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Lee, Joo-Hoon
(Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center) ;
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Park, Young-Seo
(Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center)
- 손창희 (울산대학교 의과대학 서울아산병원 소아과학교실) ;
- 이은혜 (울산대학교 의과대학 서울아산병원 소아과학교실) ;
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이주훈
(울산대학교 의과대학 서울아산병원 소아과학교실) ;
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박영서
(울산대학교 의과대학 서울아산병원 소아과학교실)
- Published : 2006.10.31
Abstract
Nephrotic syndrome in childhood is known to be associated with a hypercoagulable state and thromboembolic complications, among which cerebral venous thrombosis is a very rare and serious one, with only a few isolated reports in the literature. A 9-year-old boy with known nephrotic syndrome was admitted due to a relapse with massive proteinuria and generalized edema. He complained of a prolonged frontal headache. The enhanced brain magnetic resonance imaging(MRI) showed a high signal in the region of the superior sagittal sinus and right transverse sinus consistent with a thrombus. He was managed with steroids, cyclosporine and warfarin. His headache subsided 2 weeks later and proteinuria resolved 1 month later. An MRI 2 months later was normal. We describe this case and review the literature to emphasize the importance of recognizing this potentially life threatening complication and initiating anticoagulation therapy.