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Effect of a Pholiota adiposa Extract on Fat Mass in Hyperlipidemic Mice

  • Cho, Soo-Muk (Rural Resources Development Institute, National Institute of Agricultural Science and Technology) ;
  • Lee, Young-Min (Rural Resources Development Institute, National Institute of Agricultural Science and Technology) ;
  • Lee, Dae-Hyoung (Department of Life Science and Genetic Engineering, Paichai University) ;
  • Chun, Hye-Kyung (Rural Resources Development Institute, National Institute of Agricultural Science and Technology) ;
  • Lee, Jong-Soo (Department of Life Science and Genetic Engineering, Paichai University)
  • Published : 2006.12.31

Abstract

The purpose of this study was to investigate the effect of a Pholiota adiposa extract on fat mass in hyperlipidemic mice fed on a high-fat diet. The water extracts from P. adiposa (ASI 24018) were not affected in the total triglyceride contents and epididymal fat mass in mice fed on a high-fat diet, but the retroperitoneal fat mass decreased significantly. This result suggests that the P. adiposa extract may be a potential candidate for use as a functional food that can act as a prophylactic against hyperlipidemia. However, the P. adiposa extract showed no effect in the total triglyceride contents and epididymal fat mass.

Keywords

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