Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Preliminary Study on Effectiveness of Dexamethasone-Soaked Gelatin Sponges for Reducing Pain after Lumbar Microdiscectomy : A Randomized Controlled Trial

  • Shin, Dong-Ah (Department of Neurosurgery, Presbyterian Medical Center) ;
  • Gong, Tae-Sik (Department of Neurosurgery, Presbyterian Medical Center) ;
  • Shin, Dong-Gyu (Department of Neurosurgery, Presbyterian Medical Center) ;
  • Kwon, Chang-Young (Department of Neurosurgery, Presbyterian Medical Center) ;
  • Kim, Hyoung-Ihl (Department of Neurosurgery, Presbyterian Medical Center)
  • Published : 2006.01.30
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Abstract

Objective : A prospective, randomized, controlled clinical study is performed to verify the effectiveness of epidural dexamethasone-soaked gelatin sponges to reduce postoperative pain following lumbar microdiscectomy. Methods : Twenty-three patients (10 men and 13 women) undergoing lumbar microdiscectomy were included. Five pieces of gelatin sponge measuring $1{\times}1cm$ [Gelfoam; Pharmacia & Upjohn. Kalamazoo, MI, USA], soaked with either 5mg dexamethasone or an equal amount [2mL] of saline, were left on the decompressed nerve root after unilateral hemilami-nectomy, flavectomy and discectomy. Results : Subjective visual analog scale[VAS] scores of leg pain in the dexamethasone group on the first, third and first postoperative days [2.5, 2.5, 1.7, respectively] were significantly lower than in the control group [5.0, 4.8, 3.6][P<0.05]. No side effects related to the dexamethasone-soaked gelatin sponges were observed. Conclusion : The intraoperative application of dexamethasone-soaked gelatin sponges during lumber microdiscetomy can provide effective-postoperative analgesia without complications.

Keywords

References

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