Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Cerebrosides and Triterpenoids from the Roots of Synurus deltoides

  • Lee, Hyun-Young (College of Pharmacy, Chungnam National University) ;
  • Min, Byung-Sun (College of Pharmacy, Catholic University of Daegu) ;
  • Son, Kun-Ho (Department of Food Nutrition, Andong National University) ;
  • Chang, Hyeun-Wook (College of Pharmacy, Yeungnam University) ;
  • Kim, Hyun-Pyo (College of Pharmacy, Kangwon National University) ;
  • Kang, Sam-Sik (Natural Products Research Institute, Seoul National University) ;
  • Bae, Ki-Hwan (College of Pharmacy, Chungnam National University)
  • Published : 2006.12.30
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Abstract

A mixture of cerebrosides (1) and four triterpenoids (2 - 5) have been isolated from the hexane- and EtOAc-soluble fractions of the roots of Synurus deltoides (Ait.) Nakai (Compositae). Triterpenoid structures were determined as lupeol (2), $\beta-amyrin$ (3), $\alpha-amyrin$ (4), and ursolic acid (5). Synurus cerebrosides (1) were characterized as a common long chain base (2S,3S,4R,8E)-2-amino-8-octadecene-1,3,4-triol and fatty acyl chains; palmitic acid, (2R)-2-hydroxybehenic acid, (2R)-2-hydroxytricosanoic acid, (2R)-2-hydroxylignoceric acid, (2R)-2-hydroxypentacosanoic acid, and (2R)-2-hydroxyhexacosanoic acid. The synurus cerebrosides (1) were the first isolation from a natural source.

Keywords

References

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