Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Equine Polysaccharide Storage Myopathy in an American Paint Horse

American Paint Horse에서의 다당류저장성근질환

  • Yong, Hwan-Yul (Animal Sciences Research Center University of Missouri) ;
  • Kim, Dae-Young (Veterinary Medical Diagnostic Laboratory College of Veterinary Medicine, University of Missouri)
  • 용환율 (미주리주립대학 동물과학연구센터) ;
  • 김대영 (미주리주립대학 수의과대학 진단병리부)
  • Published : 2006.12.30
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Abstract

A 4-year-old, American Paint horse gelding with recurrent episodes of exertional rhabdomyolysis was diagnosed with equine polysaccharide storage myopathy (EPSSM). The common clinical signs were muscle weakness, loss of muscle mass, exercise intolerance, difficulty holding up limbs for farrier, sensitivity of grooming, cramping with reluctance to move and the inability to rise. Through histological examination of skeletal muscle specimens, this case was confirmed of EPSSM.

노책성 횡문근융해증의 재발을 보이는 거세된 4세령 Paint horse가 다당류저장성근질환으로 진단되었다. 말이 폐사하기전 보인 임상증상으로는 근약화, 근손실, 운동불내성, 장제시 사지를 들어올리는데 어려움이 있었고, grooming 시 민감한 반응, 이동 혹은 기립시 장애였다. 골격근 샘플의 조직검사를 통해서 말의 다당류저장성근질환으로 확진되었다.

Keywords

References

  1. Bloom BA, Valentine BA, Gleed RD, Cable CS. Postanesthetic recumbency in a Belgian filly with polysaccharide storage myopathy. Vet Rec 1999; 144: 73-75 https://doi.org/10.1136/vr.144.3.73
  2. De La Corte FD, Valberg SJ, MacLeay JM, Mickelson FR. Developmental onset of polysaccharide storage myopathy in 4 Quarter horse foals. J Vet Intem Med 2002; 16: 581-587 https://doi.org/10.1892/0891-6640(2002)016<0581:DOOPSM>2.3.CO;2
  3. McGowan CM, Menzies-Gow NJ, McDiarmid AM, Patterson-Kane JC. Four cases of equine polysaccharide storage myopathy in the United Kingdom. Vet Rec 2003; 152: 109-112 https://doi.org/10.1136/vr.152.4.109
  4. Sprayberry KA, Madigan J, LeCouteur RA, Valentine BA. Renal failure, laminitis, and colitis following severe rhabdomyolysis in a draft horse-cross with polysaccharide storage myopathy. Can Vet J 1998; 39: 500-503
  5. Quiroz-Rothe E, Novales M, Aguilera-Tejero E, Rivero JLL. Polysaccharide storage myopathy in the M. longissimus lumborum of showjumpers and dressage horses with back pain. Equine Vet J 2002; 34: 171-176 https://doi.org/10.2746/042516402776767259
  6. Valberg SJ, MacLeay JM, Mickelson JR. Exertional rhabdomyolysis and polysaccharide storage myopathy in horses. Compend Contin Educ Pract Vet 1997; 19: 1077-1086
  7. Valentine BA, Credille KM, Lavoie JP, Fatone S, Guard C, Cummings IF, Cooper BJ. Severe polysaccharide storage myopathy in Belgian and Percheron draught horses. Equine Vet J 1997; 29: 220-225 https://doi.org/10.1111/j.2042-3306.1997.tb01672.x
  8. Valentine BA, de Lahunta A, Divers TJ, Ducharme NG, Orcutt RS. Clinical and pathologic findings in two draft horses with progressive muscle atrophy, neuromuscular weakness, and abnormal gait characteristics of shivers syndrome. J Am Vet Med Assoc 1999; 215: 1661-1665
  9. Valentine BA, Divers TJ, Lavoie JP. Severe equine polysaccharide storage myopathy in draft horses: clinical signs and response to dietary therapy. Proc Am Assoc Equine Pract 1996; 42: 294-296
  10. Valentine BA, Divers TJ, Murphy DJ, Todhunter PG. Muscle biopsy diagnosis of equine motor neuron disease and equine polysaccharide storage myopathy. Equine Vet Educ 1998; 10: 42-50 https://doi.org/10.1111/j.2042-3292.1998.tb00846.x
  11. Valentine BA, Habecker PL, Patterson JS, Njaa BL, Shapiro J, Holshuh HJ, Bildfell Rl, Bird KE. Incidence of polysaccharide storage myopathy in draft horse-related breeds: a necropsy study of 37 horses and a mule. J Vet Diagn Invest 2001; 13: 63-68 https://doi.org/10.1177/104063870101300112
  12. Valentine BA, Hintz HF, Freels KM, Reynolds AJ, Thompson KN. Dietary control of exertional rhabdomyolysis in horses. J Am Vet Med Assoc 1998; 212: 1588-1593
  13. Valentine BA, McDonough SP, Chang YF, Vonderchek AJ. Polysaccharide storage myopathy in Morgan, Arabian, and Standardbred related horses and Welsh-cross ponies. Vet Pathol 2000; 37: 193-196 https://doi.org/10.1354/vp.37-2-193
  14. Valentine BA, Reynolds AJ, Wakshlag J, Ducharme NG. Muscle glycogen, myopathy, and diet. World Equine Vet Rev 1997; 2: 27-31
  15. Valberg SJ, Townsend D, Mickelson JR. Skeletal muscle glycolytic capacity and phosphofructokinase regulation in horses with polysaccharide storage myopathy. Am J Vet Res 1998; 59: 782-785
  16. Valentine BA, Van Saun RJ, Thompson KN, Hintz HF. Role of dietary carbohydrate and fat in horses with equine polysaccharide storage myopathy. J Am Vet Med Assoc 2001; 219: 1537-1544 https://doi.org/10.2460/javma.2001.219.1537