Journal of the korean academy of Pediatric Dentistry (대한소아치과학회지)
- Volume 33 Issue 1
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- Pages.13-24
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- 2006
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- 1226-8496(pISSN)
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- 2288-3819(eISSN)
Effects of epigallocatechin gallate on $CoCl_2-induced$ apoptosis in PC12 cells
PC12 세포에서 $CoCl_2$ 유발 세포자멸사에 대한 epigallocatechin-gallate의 역할
- Mo, Hyun-Chul (Department of Pediatric Dentistry, School of Dentistry, Chonnam National University and Dental Research Institute) ;
- Choi, Nam-Ki (Department of Pediatric Dentistry, School of Dentistry, Chonnam National University and Dental Research Institute) ;
-
Kim, Seon-Mi
(Department of Pediatric Dentistry, School of Dentistry, Chonnam National University and Dental Research Institute) ;
- Kim, Won-Jae (Department of Oral Physiology, School of Dentistry, Chonnam National University and Dental Research Institute) ;
- Yang, Kyu-Ho (Department of Pediatric Dentistry, School of Dentistry, Chonnam National University and Dental Research Institute)
- 모현철 (전남대학교 치과대학 소아치과학교실) ;
- 최남기 (전남대학교 치과대학 소아치과학교실) ;
-
김선미
(전남대학교 치과대학 소아치과학교실) ;
- 김원재 (전남대학교 치과대학 구강생리학교실 및 치의학연구소) ;
- 양규호 (전남대학교 치과대학 소아치과학교실)
- Published : 2006.02.28
Abstract
Neuronal apoptotic events, consequently resulting in neuronal cell death, are occurred in hypoxic/ischemic condition. This cell death has been shown to be accompanied with the production of reactive oxygen species (ROS), which can attack cellular components such as nucleic acids, proteins and phospholipid. However, the underlying mechanisms of apoptosis induced in hypoxic/ischemic condition and its treatment methods are unsettled. Cobalt chloride
신경세포자멸사는 저산소 및 허혈환경에서 일어나며 이러한 세포죽음은 reactive oxident species (ROS) 생성을 동반함이 알려져있다. 그러나, 저산소 및 허혈환경에서 일어나는 세포자멸사의 기전 및 그 치료방법은 아직 정립되어 있지 않다.
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