Korean Journal of Clinical Pharmacy (한국임상약학회지)
- Volume 16 Issue 2
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- Pages.81-85
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- 2006
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- 1226-6051(pISSN)
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- 2508-786X(eISSN)
Comparison of Antibiotic Regimens for the Treatment of Community Acquired Pneumonia
원외획득 폐렴 환자치료에서 항생제 regimen 별 효능비교
- Moon, Hong-Seop (Department of Pharmacy, Chosun University Hospital) ;
- Choe, In (Department of Pharmacy, Chosun University Hospital) ;
- Lee, Seung-Il (Internal Medicine, Chosun University Hospital)
- Published : 2006.12.30
Abstract
Community acquired pneumonia(CAP) is the most prevalent disease among pneumonia patients and progressed to severe pneumonia. A retrospective study was performed to evaluate antibiotic regimens according to guidelines of Infectious Disease Society of America. From January to October 2005, chart review of 50 patients with CAP was peformed in terms of microbiology and laboratory data of each regimen. Temperature, WBC count, ALT, AST and alkaline phosphatase of each patient were examined for liver toxicity. In three patients received levofloxacin appeared to have normalized temperature and improved cough. The patients who received cefmetazole -aminoglycoside appeared to have worsen LFT(Liver function test). Many patients in flomoxef-aminoglycoside group received mechanical ventilation because of the basis diseases like tuberculosis, diabetes mellitus and hypertension. In conclusion, antibiotic therapy for the treatment of CAP should be selected according to tolerance, bacteria and severity of disease.