Journal of the Korean Society of Food Culture (한국식생활문화학회지)

Korean Society of Food Culture (한국식생활문화학회)
권호 표지
DOI QR코드

DOI QR Code

Effects of Lotus (Nelumbo Nucifera Gaertner) Leaf Powder on Lipid Concentrations in Rats Fed High Fat Diet Rats

연잎 건분이 고지방식이를 먹인 흰쥐의 지질 농도에 미치는 영향

  • Shin, Mee-Kyung (Dept. of Food of Nutrition, College of Human Environmental Science, Wonkwang University) ;
  • Han, Sung-Hee (Dept. of Food of Nutrition Wonkwang Health Science College)
  • 신미경 (원광대학교 생활과학대학 식품영양학과) ;
  • 한성희 (원광보건대학 식품영양과)
  • Published : 2006.04.30
Download PDF
⟨ Previous Next ⟩

Abstract

The effects of Lotus (Nelumbo nucifera Gaertner) leaf dry powder on serum lipid concentrations were evaluated in rats. Forty-eight male Sprague-Dawley rats were divided into six groups and fed high fat diets for sis weeks. Experimental groups were following diets; Control group (CON), 40 % animal and plant high fat group (AHF and PHF) control with 2% Lotus leaf dry powder group (CLDP), animal and plant high fat diets with 2% Lotus leaf powder group (AHFLDP, PHFLDP). Tissue weights of liver, heart, kidney, spleen and lung of AHF group exposed rats were decreased by PHFLDP groups. The concentrations of serum triglyceride in rats fed the CLDP and PHFLDP group were lower than those in other groups. The concentrations of total cholesterol in CLDP and PHFLDP group the were lower than those in AHF groups. The concentrations of HDL-cholesterol in serum of the CLDP and PHFLDP groups were significantly higher than those of other groups. The levels of LDL-cholesterol in serum of the CLDP and PHFLDP groups were tended to be lower than those of other groups. GPT and GOT were decreased in CLDP and PHFLDP groups and than in the AHF group. LDHase was lower in CLDP and PHFLDP groups than in the AHF group. These results suggest that 2% Lotus leaf dry powder groups may reduce elevated levels of serum lipid concentrations in rats fed high fat.

Keywords

References

  1. Allred JB. 1990. Elevated blood cholesterol, A risk factor for heart disease that decrease with advanced age. J Am Diet Assoc, 90(4): 574-576
  2. Anna P, Milena B, Marco S, Nadia P, Gian FM, Clandio G. 2002. Inhibition of plated aggregation and eicosanoid production by phenolic components of olive oil. Thrombosis Res, 78(3): 151-266 https://doi.org/10.1016/0049-3848(95)00043-7
  3. Bergmeyer HU. 1974. Methods of enzymatic analysis. Verlag Chemie. Academic Press Weinheim, 1: 20-28
  4. Buring JE, Hennekens CH. 1977. Antioxidant vitamins and cardiovascular disease. Nutrition reviews, 55(1): 53-60 https://doi.org/10.1111/j.1753-4887.1997.tb06103.x
  5. Chae S. 1988. Biochemist for life Science. JI-Gu Publishing Co. pp 15-55
  6. Chung HY, Takako Y. 1995. Studies on antioxidative and antimutagenic mechanism of epicatechin 3-O-gallate isolated from green tea. The 3rd international symposium on greed tea. Seoul Korea, pp 65-81
  7. Hagulund O, Loustarinen R, Wallin R, Wibell I, Saldeen T. 1991. The effect of fish oil on triglycerides, cholesterol, fibrinogen and malondialdehyde in humans supplemented with vitamin. Eur J Nutr, 12(6): 165-172
  8. Haenen GR Paquay JB, Korthouwer RE, Bast A. 1997. Peroxynitrite scavenging by flavonoids. Biochemical & Biophysical Research Communications, 236(3): 591-593 https://doi.org/10.1006/bbrc.1997.7016
  9. Hera Y, Nakamira H. 1977. Effect of tea flavonoid supplementation on the susceptibility of low density lipoprotein to oxidative modification. Am J Clin Nutr, 66(2): 261-266
  10. Husain SR, Cillard J, Cillard P. 1987. Hydroxyl radical scavengers activity of flavonoids. Phytochmistry, 26(9): 2489-2491 https://doi.org/10.1016/S0031-9422(00)83860-1
  11. Ishikawa T, Suzukaea M, Ito T, Yoshoda H, Ayaori M, Nishiwaki M, Yonemura H, Ayaori M, Nishiwaki M, Yonemura A Hera Y, Nakamira, H. 1977. Effect of tea flavonoid supplementation on the susceptibility of low density looprotein to oxidative modification, Am J Clin Nutr. 66(2)
  12. Kang YH, Park YH, Ha TY, Moon KD. 1996. Effects of pine nedle extracts on serum and liver lipid contents in rats fed high fat diet. J Korean Soc Food Nutr, 25(3): 367-373
  13. Kim YJ. 1977. The protect the living organ from free radicals and the failure of protection age-related disease. Bulletin of food technology, 10(2): 4-26
  14. Kim SH. 1977. Oil seeds refining & oil consumption pattern. The Korean Nutrition Society, pp 546-552
  15. Ki HY Song SW, Ha CS, Han SS. 1993. Effects of the population density on growth and various physiological values of Sprague-Dawely rats. Korean Jab Ani Sci, 9: 71-82
  16. Kim ES, Kim MY. 1999. Effects of dried leaf powders and etanol extracts of persimmon, green tea and pine neddle on lipid metabolism and antioxidative capacity in rats. Korean J Nutrition, 32(4): 337-352
  17. Kim YS, Jeon SS, Jung ST. 2002. Effect of Louts powder on the baking quality of white bread korean. J Soc Food Cookery Sci, 18(4): 413-425
  18. Lim SS, Lee JH. 1977. Biological activity of the souble extreacts from artemisia princeps var orientalis acted on cardivascula system. Korean J Nutr, 30(1): 12-18
  19. Lee SH, Park YB, Choi MS. 1998. The effect of dietary citrus flavonoid supplementation on cholesterol biosynthesis control in rats. The Autummol symposium of Korean Nutr Association, pp 79-90
  20. Mazur A, Remesy C, Gueux E, Levrat MA, Demigne C. 1990. Effects of diets rich in fermentable carbohydrates on plasma lipoprotein levels and on lipoprotein catabolism in rats. J Nutr, 120(9): 1037-1045 https://doi.org/10.1093/jn/120.9.1037
  21. Morel I, Lescoat G, Cogrel P, Sergent O, Pasdelop N, Brisst P, Cillard P, Cillard J. 1993. Antioxidant and iron-chelated activities of the flavonoids catechin, quercretin and diosmetin on iron-loaded rat hepatocyte cultures. Biochem Pharmacol, 45:13-19 https://doi.org/10.1016/0006-2952(93)90371-3
  22. Nam BS, Lye YJ, Jin HH, Ha KY. 2002. Effects of green tea consumprion on serum lipid profiles. The korean Nutr society, 35(8): 854-862
  23. Nishmura N, Taniguchi Y, Kiriyama S. 2000. Plasma cholesterol-lowering effect on rats of dietary fiber extracted from immature plants. Biol Biotechnol Biochem, 64(12): 2543-2551 https://doi.org/10.1271/bbb.64.2543
  24. Nicolle C, Cardinault N, Gueux E, Jafferlo L. Rock E, Mazur A, Amouroux P, Remesy C. 2004. Health effect of vegetable-based diet; lettuce consumption impressive cholesterol metabolism and antioxidant status in the rat. Clin Nutr, 23: 605-614 https://doi.org/10.1016/j.clnu.2003.10.009
  25. Park SH, Hyun JS, Shin EH, Han JH. 2005. Functional evaluation of lotus root on lipid profile and health improvement. J East Asian Soc Dietary Life. 15(3): 257-263
  26. Present knowledge in nutrition 8th editon. 2002. The Korean Nutrition Society Seoul, pp 553-560
  27. Robak J, Gryglewski RJ. 1988. Flavonoids are scavegers of superoxide anions. Biochemicals Pharmacology, 37(5): 837-841 https://doi.org/10.1016/0006-2952(88)90169-4
  28. Reitman, S, Frankel, S. 1957. A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminases. Amer J Clin Pathol. 28: 56-60 https://doi.org/10.1093/ajcp/28.1.56
  29. Shin DH. 1992. The research and prospect of natural antioxidants. Bulletin of food technology, 8(2): 28-33
  30. Shin DH, Kim IW, Kwon KS, Kim MS, Kim MR, Choi U. 1999. Chemical composition of lotus seed(Nelumbo nucifera Gaertner) and their lipid and protein composition J. Korean Soc Food Sci. Nutr, 28(6): 1187-1190
  31. Shoji N, Umeyama H, Saito N, Iuchi A, Takemoto T. 1987. Asimilobine and lirinidine serotonergic receptor a antagonists from nelumbronucifera. J Natural products. 50: 773-774 https://doi.org/10.1021/np50052a044
  32. Sicat R, Sable-Amplis R. 1987. Reduction of cholesterol transported in apo B-rich lipoproteins in spontaneously hydrocholesterolemic hamsters fed an apple supplemented diet. Ann Nutr Metab, 31(1): 1-8 https://doi.org/10.1159/000177242
  33. Stamler J. 1981. Introduction to risk faction in coronart artery disease in medical communication. Northfield, pp 1-3
  34. Statistical office 2004: Yearbook of death cause statist Korea
  35. Torel J, Cillard J, Cillard P. 1986. Antioxidant activity of flavonoids and reactivity with peroxyl radical. Phytochemistry, 25(2): 383-385 https://doi.org/10.1016/S0031-9422(00)85485-0
  36. Yoon SH, Joo CN. 1993. Studt on the preventive effect of ginsenosides againt hypocholesterolemia and its mechanism. Kor J Ginseng Sci, 17(1): 1-12
  37. Yuk CS. 1990. Coloured midicinal plants of korea. Academy book Co Seoul Korea, pp. 219-230
  38. Wroblewski F, Ladue JS. 1955. Lactic dehydrogenase activity in Blood. Proc Soc Exper Biol Med. 90: 210-250
  39. Wu MJ, Wang L and Weng CY. 2003- Antioxidant activity of menthanol extract of the Louts leaf(Nelumbo nucifera Gertn). The American Journal of Chinese Medicine,31(5): 687-69 https://doi.org/10.1142/S0192415X03001429