Journal of the Korean Society of Food Culture (한국식생활문화학회지)

Korean Society of Food Culture (한국식생활문화학회)
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Effects of Dietary Dae-Chu (Rhamnace ziziphus), Onion (Allium cepa L.), Mixture Extract on Serum Composition in Rats

대추, 양파, 혼합추출물이 흰쥐의 혈청조성에 미치는 영향

  • Cho, Young-Ja (Major in Food & Nutrition, Mokpo National University) ;
  • Park, Hee-Jin (Home Economics Education, Mokpo National University) ;
  • Ju, Sung-Mee (Home Economics Education, Mokpo National University) ;
  • Hou, Won-Nyoung (Horticuitural Science, Mokpo National University)
  • 조영자 (목포대학교 생활과학부 식품영양) ;
  • 박희진 (목포대학교 교육대학원 가정교육) ;
  • 주성미 (목포대학교 교육대학원 가정교육) ;
  • 허원녕 (목포대학교 생물산업학부 원예과학)
  • Published : 2006.02.28
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Abstract

The purpose of this study was to investigate the effect of dietary dae-chu(Rhamnace ziziphus, A), onion(Allium cepa L., O), mixture extracts (mulberry leaf, licorice root, pine needle, angelica gigas, jujube, onion, M) on serum glucose, lipid, enzyme, phosphorus levels in rats (Sprague-Dawley male rats, $357.03{\pm}7.08g$). Serum calcium of onion group was significantly decreased (p<0.05), but mixture extracts group of Cl (p<0.05) and TBIL (total bilirubin, p<0.05) were significantly increased. Serum glucose, total cholesterol, HDL-cholesterol and triglyceride were increased experimental rats than those of the normal rats. Mixture extracts was better than other groups for lipid metabolism. Also, GPT(glutamic pyruvic transaminase) and GOT(glutamic oxaloacetate transaminase) of onion extracts were protected to liver. So mixture and onion extracts were good drink for health.

Keywords

References

  1. Annual report on the cause of death statistics. National Statistical Office, Korea 2001
  2. Anderson JW, Deakins DA, Floore, Smith BM, Whitis SE. Dietary fiber and coronary heart disease. Crit Rev Food Sci Nutr 29: 95-147,1990 https://doi.org/10.1080/10408399009527518
  3. Bang HO and Dyerberg J. Plasma lipid and ischemic heart disease in Grenland Eskimos. Adv Nutr Res 3:1-9, 1980
  4. Kin HK Kim YE, Do JR Lee YC, Lee BY. Antioxidative activity and physiological activity of some Kor medical plants. Kor J Food Sci Technol 27: 80-85, 1995
  5. Choi U, Shin DH, Chang YS, Shin JI. Screening of naairal antioxidant from plants and antioxidant effect. Kor J Food Screening Technol 24: 142-148, 1992
  6. Park PS, Lee PR ,Lee MY. Effect onion juice on ethanol-induce hepartic lipid peroxidantion in rats. J Kor Soc Food Sci Nutr 23: 750-756, 1994
  7. Lee YK, Lee HS. Effect of onion and ginger on the peroxidation of mackerel during from storage. J Kor Soc Food Sci Nutr 19: 321-329,1990
  8. Yoon JY, Song MR, Lee SR. Comparison of antithiamine activities of wild vegetables. Kor J Food Sci Technol 20: 808-811,1998
  9. Kang YH, Park YK, Oh SR, Moon KD. Studies on the physiological functionality of pine needle and mugwort extract. Kor J Food Sci Technol 27: 978-984, 1995
  10. Miquel J, Quintanilla AT, Weber H. Handbook of free radicals antioxidants in biomedicine CRC Press, Vol a pp. 223-244,1989
  11. RCNR, Treatise on Asian Herbal Medicines.Vol. 1, pp. 11-113, Research Center of Natural Resources, Seoul, Korea, 2003
  12. Baek KU, Lee SY, Han DS. Studies on con(m)ponents of the fufube in Korea. Research of Bull Kangwon Nat Unir 3: 22-26,1900
  13. Rhee YK, Kim DH, Han MJ. Inhibitory effect of Zizyhi frutus on glucuronidase and tryptophanase of human intesteria. Kor J Food Sci Technkl, 30: 199-205
  14. NA HS, Kim Ks, Lee MY . Effect of Jujube Methanol Extract on the Hepeatoxicity in CC14-Treated Rats. J. Kor Soc. Food Sci. Nutr, 25(5): 893-855,1996
  15. Lee YG Cho Effect of Jujube methanol extract on benzo (a) pyrend induced hepatotoxicity. J kor soc Food Sci 24: 127, 1996
  16. Deiaqis P, Mazza G. Functional vegetable products. In: Functional Foods, Biochemical and processing Aspects. Mazza G (ed). Lancaster, PA, USA, pp. 193-233,1998
  17. Yuk CS, Sim JH, Kim HG, Nam JY. Chinese medicine, kang mung co. pp 394,1992
  18. Block E. Antithrombotic organosulfur compounds from garlic. J Am Soc 108: 1045-1050,1986
  19. Ali M, Thomon M, Afzal M.Garlic and onions:their effect on eicosanoids metabolism and its clinical relevance. Prostaglandins, Leukotrienes and Essential Fatty Acids 52( 2): 55-73, 2000
  20. Hanley AB, Fenwick GR. Cultivated alliums. J plant Foods 6: 211-238,1985 https://doi.org/10.1080/0142968X.1985.11904312
  21. Breu W, Dorch W. Allium cepa L (onion). Chemistry analysis and phamocolgy, Econ Med plant Res 6: 116-147, 1994
  22. Kimura M, Chen F, Nakashima N, Kimura I, Asano A, Koya S, Anti-hyperflvcemic of effect of N-containing sugars derived from mullberry leaves in streptoztocin-induced diabetic mice. J Traditonal Med 12: 214-216, 1995
  23. Kim AJ, Yuh CS. The development of functional food products manufactured with mulberry leaf. Food sci and industry, 37: 24, 2004
  24. Jang MJ , Rhee. SJ. Hypoglycemic Effects of Pills Made of Mullberry Leaves and Silkwonn Powder in Streptozotocin-Induced Diabetic Rats, J Kor Soc Food Sci Mutr 33(10): 1611-1617,2004 https://doi.org/10.3746/jkfn.2004.33.10.1611
  25. Basnet P, Kadota s, Terashima S, Simazu S, Namba T. New 2-arylbenzofuran derivatives from hypoglycemic activity-bearing fractions of Morus insignis. Cham Phann Bull 41: 1238-1243, 1933
  26. Asano N. Oseki K, Tomioko E, Kizu H, Matsui K. N-containing sugars from Morus alba and their glycosidase inhibitory activities. Carbobydrate Research 259: 243-255, 1994 https://doi.org/10.1016/0008-6215(94)84060-1
  27. Kimura M. Chen F, Nakashima N, Kimura I, Asano N, Koyas. Antihyperglycemic effect of N-containing sugars derived from mulberry leaves in streptozotocin-induced diabetic mice. J Traditional Medicine 12: 214-219, 1995
  28. Lee JS, Choi MH. Blood glucose-lowering effects of Mori folium. Yakhak Hoeji 39: 367-372,1995
  29. Kim MS, Choue RW, Chung RW, Koo . Blood glucose lowering effects of mulberry leaves and silkwonn extracts on mice fed high-carbohydrate diet. Kor J nutr 51: 117-121, 1998
  30. Kim SY, Ryu KS, Lee WC, Ku HO, Lee KR. Hypoglycemic effect of mulberry leaves with anaerobic treatment in alloxan-induced diabetic mice. Kor J Phamacogn 30: 123-129, 1999
  31. Kim SY, Lee WC. The effects of mulberry on inhibition of HMG-Co A reductase. RDA J Agric Sci 38: 133-139, 1996
  32. Kim SY, Lee WC, Kim HB, Kim AJ, Kim SK. Antihyperlipidemic effects of methanol extracts from mulberry leaves in cholesterol-induced hyperlipidemia rats. J Kor Soc Food Sci Nutr 27:1217-1222,1998
  33. Yengc, Wu SC, Duh PD. Extraction and identification of antioxidant components from the leaves of mulberry(Morus alba L.O, J Agric Food Chem 44:1687-1690,1996 https://doi.org/10.1021/jf9503725
  34. Kim SY, Gao JJ, IEE wc, Ryu KS, Kim YC. Antioxidative flavonoids from the leaves of Morus alba Arch Pharm Res 22: 81-85, 1999 https://doi.org/10.1007/BF02976442
  35. Doi K, Kojima T, Fujimoto Y. Mulberry leaf extract inhibits the oxidative modification of rabbit and human low density lipoprotein. Biol Pharm Bull 23: 1066-1071, 2000 https://doi.org/10.1248/bpb.23.1066
  36. Chae JY, Lee JY, Hoang IS, Whangbo D, Choi PW, Lee WC, Kim SY, Choi SW, Rhe SJ. Analysis of Functional Components of Different Mulberry Cultivars. J Kor Soc Food Sci Nutr 32(1): 15-21, 2003 https://doi.org/10.3746/jkfn.2003.32.1.015
  37. Onogi A, Osawa K, Yasuda H, Sakai A, Morita H, Tokawa H Flavonol glycosides from the leaf Morus alba Shoyakugaku Zassh 47: 423-425,1993
  38. Shin KH, Young Hs lee Tw, Choj JS Studies on the chemical xomponent and antioxidative effects of Sola-mum Lyraaim Kor J Pharma 26:130-138,1995
  39. Kim MW, Ahn MS Lim YH The antioxidative ac-tivities of mulberry leaves extracts on edible soybean oil, Kor J Food Culture 18: 1-8, 2003
  40. Yen GC, Wu SC, Duh PD Extraction and identification of anti-oxidant components from the Leaf mul- berry (Moms alba L) J Bio Chem 261: 12879-12882, 1996
  41. Kang YH, Park YK, Ha TY, Moon KD. Effects of pine needle extracts on serum and liver lipid contens in rats fed high fat diet. J Kor Soc Food Nutr 25: 374-378, 1996
  42. Kim SM, kim EJ, cho YK, sung YK. Antioxidants of pine needle extracts according to preparation method, kor J food Sci Technol 31: 527-534,1999
  43. Kim JJ, song HK, Han CH. Antifungal activities of extracts from various parts of the genus pinus trees. Kor Soc Agric chem Biotecnol 44(4): 269-272, 2001
  44. Park JK Hanbang Daewejeun Dongyang Jonghab tong-singyoyukweon Daegu P.134-136, 1984
  45. MBC Hankook mingabyobodaejeun Kumbak pub Co Seoul P21-25, 1988
  46. Kang YH Park YK, Ha TY Moon KD Effects of Pine needle extracts on seaim and ilver lipid contents in rat fed high fat diet J kor Soc Food NUtr 25; 367-373, 1996
  47. Kang YH Park YK, Ha TY Moon KD Effects of Pine needle extracts on enzyme activities of serum and liver liver morphlolgy in rats fed high foat diet J kor Soc Food Nutr 25: 374-378,1996
  48. Choi My Choi EJ, Lee E, Rhim TJ, Cha BC Park HJ. Antimicrobial .activites of pine needle( Pinis densiflora seib er Zicc) Kor J Appl Microbiol Biotechnol 25:293-297,1997
  49. Park YG. Rhamnace ziziphus. Kor), VOl, 6, P32, 1993
  50. Park JC, Yee ST. Functional Food and Bioactive Constituents from Oriental Medicine Resources. Food Industry 5(3): 27-37, 2000
  51. Byun PH, Kim WJ, Yoon SK . Effects of extractio codition goditoons on the funtional properties of galic extracts. Kor J Food Sci Technol 33: 507-513, 2001
  52. Duncan DB. Multiple rarnge test and murtiple F tests Biometrics 11: 1-42, 1955 https://doi.org/10.2307/3001478
  53. Popovtzer MM, Disorders of calcium, phosphorous, vitamin D and parathyroid hormone activity. In: Schrie RW ed. Renal and electro-activity disorders. Little Brown, Boston 1976
  54. Ayachi S. Increased dietary calcium lowers blood pressure in the spontaneously hypertensive rat. Metabolism 28(12): 1234-1238,1979 https://doi.org/10.1016/0026-0495(79)90136-7
  55. Castenmiller JJM, Mensink RP, vin der Heijden L, Kouwenhoven T, Hautvast JGAJ, de Leeuw PW, Schaafsma G, The effect of dietary sodium on urinary calcium and potassium excretion in normotensive men with different calcium intakes. Am J Clin Nutr 41: 52-60, 1985 https://doi.org/10.1093/ajcn/41.1.52
  56. Wasler M. Calcium clearances as a function of sodium clearances in the dog. Am J Physiol 200(5): 1099-1164.1961
  57. Cha JY, Homg SS, Cho YS, Kim DJ. Effeats of different dierarg fats and fibers on the lipid concentra tions of liver and serum and bio chemi cal Index in Rats, J kor soc foo Sci Nutr 32(8): 1377-1384, 2003 https://doi.org/10.3746/jkfn.2003.32.8.1377
  58. Wroblewski F, La Due JS. Serum glutamic pyrvic transaminase in cardiac and hepayic disease. Proc Exp Biol Med 91: 569,1956 https://doi.org/10.3181/00379727-91-22330
  59. Sheo HJ, Jung DL. The effects of onion juice on seaim lipid levels in rats. J Kor Soc Food Sci Nutr 25:1164-1172,1997
  60. Sheo HJ, Jung DL, the effects of onion Juice on serum lipid levels inrats. J Kor Soc Food Nutr 25(6): 1164-1172,1997
  61. Kang JA, Kang JS. Effect of garic and onion on plasma and liver cholesterol and triacylglycerol and platelet aggregation imrats fed basal or cholesterol supplemented diets. Kor J Nutr 30(2): 132-138, 1997
  62. The association of Korean clinical pathology. The clinical pathology. Kor Medicine Co, Seoul, pp.40-79,1994
  63. Ortho clinical Diagnostics. The reference intervals in biochemical analysis of laboratory animal. Johnson & Johnson Co, New Yo가, p. 13, 2001
  64. Zimmerman, H, J: Chemical hepatic injury and its derection, In 'Toxicology of the liver' Plaa G land Hewitt W R(eds), Raven Press 22, P 1, 1981
  65. Wroblewski F and La Due J. S: Serum glutamic-pyruvic transaminase in cardiac and hepatic disease proc Exp Biol Med 91 569,1956
  66. Yoon JK. Atimycin D, prednisolone and xanthine oxidase Ke mung University 7: 113, 1988
  67. Hays AW. Principles and methods of toxicology, Raben Press, New York p407, 1982
  68. Lee JH, Park KS. Effect of Ganodema lucidum on the liver function and metabolism in alcohol-consuming rats. Kor J Nutr 32: 519-525,1999
  69. Zimmerman HJ. Chemical hepatic infury and its detection. In Toxicology of the liver, Plaa GI, Hewitt WR(eds), Raven Press, 22, pp.1, 1981
  70. Koo, BK,. Chung, JM., Lee HS. Biochemical evaluation of nutritional status of protein and liped in patients with alcoholic liver disease. Kor J. Food Sci. Nutr,. 27, 1236-1243, 1998