Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Studies on Pharmaceutical Quality of Oriental Medicinal Preparations (I) - Studies on Decoction of Nokyong-Sagunja-Tang -

한방방제의 제제학적 연구(1) - 추출방법에 따른 녹용사군자탕의 비교 -

  • Choi, Hyuck-Jae (East-West Medical Research Institute, Kyung Hee University) ;
  • Kim, Eun-Jin (East-West Medical Research Institute, Kyung Hee University) ;
  • Kim, Sung-Soo (College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Nam-Jae (East-West Medical Research Institute, Kyung Hee University)
  • 최혁재 (경희대학교 동서의학연구소) ;
  • 김은진 (경희대학교 동서의학연구소) ;
  • 김성수 (경희대학교 한의과대학) ;
  • 김남재 (경희대학교 동서의학연구소)
  • Published : 2006.09.30
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Abstract

Decoction of oriental medicinal preparation is prepared in various manners, and changes of chemical constituents might be occurred depending on the processing techniques. The present study was undertaken to investigate the phγsio-chemical and pharmacological equivalence between two extraction methods of Nokyong-sagunja-Tang. Samples were Prepared as follows ; Sample-I was prepared by simultaneously extracting Sagunja-Tang and velvet antler in one vessel. Sample-lI was prepared by adding velvet antler exact to the water extract of Sagunja-Tang. Both sanples showed similar results of physiochemical parameters such as pH, yield, TLC and HPLC chromatogram, and contents of ginsenoside $Rb_1$ and glycyrrhizin. Also, there were little different between two samples in pharmacological effects such as DPPH free radical scavenging effect, and inhibitory effects on xanthine oxidase, hyaluronidase, trypsin, TBA-Rs formation and hemolysis in vitro. And both samples showed no significant difference in antifatigue activities in mice. These results suggest that there might be little difference between two extraction process when velvet antler added to Sagunia-Tang.

Keywords

References

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