Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Studies for Component Analysis and Biological Evaluation in Picrasma quassioides (D.Don) Benn. Extracts

소태나무(Picrasma quassioides (D.Don) Benn.)의 성분분석과 생리활성 평가

  • Jin, Ying-Shan (Division of Biotechnology, Kangwon National University) ;
  • Yin, Yu (Division of Biotechnology, Kangwon National University) ;
  • Shin, Tae-Heum (Gangwon Research Institute of Health and Environment) ;
  • Sa, Jae-Hoon (Gangwon Research Institute of Health and Environment) ;
  • Wang, Myeong-Hyeon (Division of Biotechnology, Kangwon National University)
  • 김영선 (강원대학교 생명공학부) ;
  • 윤유 (강원대학교 생명공학부) ;
  • 심태흠 (강원도 보건환경연구원 식의약품분석과) ;
  • 사재훈 (강원도 보건환경연구원 식의약품분석과) ;
  • 왕명현 (강원대학교 생명공학부)
  • Published : 2006.03.30
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Abstract

This study investigates the chemical components and biological activities in Picrasma quassioides (D.Don) Benn. extracts for the purpose of developing natural pharmaceutical products. The proximate components in Picrasma quassioides (D.Don) Benn. extracts were 81.56% of carbohydrate, 5.80% of crude fat, 7.75% of crude protein, and 2.07% of crude ash. Calcium was the most predominant mineral and followed phosphorus, potassium, sodium, and magnesium, in a decreasing order. The content of the unsaturated fatty acids, such as oleic acid, linoleic acid, and linolenic acid, was find to be higher than those of saturated fatty acids. Water and methanol extract exhibited antioxidative activity with $IC_{50}$ of $128{\mu}g/ml$ and $144{\mu}g/ml$, respectively, suggesting that the extracts are the major biological component in Picrasma quassioides (D.Don) Benn. extracts. The ${\alpha}-glucosidase$ inhibitory activity showed that methanol and water extract were the high inhibitory activity. Considering these results, water extracts of Picrasma quassioides (D/Don) Benn. showed the possibility that they can be used as a new material for natural pharmaceutical products.

Keywords

References

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