Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Studies on the Anti-Inflammatory and Analgesic Effects of Extracts from Marine Sponges

  • Published : 2006.06.01
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Abstract

Two specimens of sponges collected from Red Sea, Egypt, were investigated for their contents of secondary metabolites. The crude extracts of the sponges were tested for their anti-inflammatory and analgesic effects. The toxic effects of the extracts of the two marine sponges were studied. $LD_{50}$ determination revealed that the investigated extracts of 'Igernella and Ircinia spp' were 4.69 and 134.7 mg/l00 g b.wt., respectively, when injected intraperitoneally in mice. The toxic signs were recorded within the first 24 hrs after injection. Also the two marine sponges extracts showed significant anti-inflammatory and analgesic effects.

Keywords

References

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