Herbal Formula Science (대한한의학방제학회지)

The Korean Medicine Society for the Herbal Formula Study (대한한의학방제학회)
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Effect of Dioscoreae Rhizoma Extract on Sperm Motility Reduction

산약(山藥)이 정자 운동성 저하에 미치는 영향

  • Chang, Mun-Seog (Department of Medicine, Division of Newborn Medicine, Children's Hospital and Harvard Medical School) ;
  • Oh, Myung-Sook (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Lee, Byong-Hee (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Yang, Woong-Mo (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Won-Nam (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Do-Rim (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Hyang-Mi (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Park, Eun-Hwa (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Park, Wan-Su (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Yun-Kyung (College of Pharmacy, Wonkwang University) ;
  • Park, Seong-Kyu (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University)
  • 장문석 (하버드대학교 의과대학 소아병원) ;
  • 오명숙 (경희대학교 한의과대학 처방제형학교실) ;
  • 이병희 (경희대학교 한의과대학 처방제형학교실) ;
  • 양웅모 (경희대학교 한의과대학 처방제형학교실) ;
  • 김원남 (경희대학교 한의과대학 처방제형학교실) ;
  • 김도림 (경희대학교 한의과대학 처방제형학교실) ;
  • 김향미 (경희대학교 한의과대학 처방제형학교실) ;
  • 박은화 (경희대학교 한의과대학 처방제형학교실) ;
  • 박완수 (경희대학교 한의과대학 처방제형학교실) ;
  • 김윤경 (원광대학교 한약학과) ;
  • 박성규 (경희대학교 한의과대학 처방제형학교실)
  • Published : 2006.06.30
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Abstract

The purpose of this study was to investigate the effect of water extract of Dioscoreae Rhizome on the reproduction activity of Wistar male rat. The group treated with 1.0 g/kg/day oral administrations of water extract of Dioscoreae Rhizoma (SK0l6) during 8 weeks was compared with the normal group. Sperm count, sperm motility, body weight, and testis weight were investigated in two groups. Sperm count. body weight, and testis weight of two groups did not show the significant difference. But sperm motility of the treated group was reduced significantly (the normal group: 56.43 %, SK0l6 group: 53.47 %, p < 0.05). According to the results, SK0l6 have no effects on sperm count, body weight. and testis weight but reduced sperm motility significantly.

Keywords