Archives of Pharmacal Research

  • 제29권9호
  • /
  • Pages.786-794
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  • 2006
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  • 0253-6269(pISSN)
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  • 1976-3786(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Glucose-lowering Effect of Powder Formulation of African Black Tea Extract in $KK-A^y/TaJcl$ Diabetic Mouse

  • Shoji, Yoko (Department of Microbiology, St. Marianna University School of Medicine) ;
  • Nakashima, Hideki (Department of Microbiology, St. Marianna University School of Medicine)
  • 발행 : 2006.09.01
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초록

We observed the suppressive effect of a powder formulation of African black tea extract prepared from the leaves of Camellia sinensis on type 2 non-insulin dependent diabetic mice, $KK-A^y/TaJcl$. Black tea extract significantly showed suppressive effect of the elevation of blood glucose on oral glucose tolerance test of 8 week-old $KK-A^y/TaJcl$ mice (p<0.05). Long-term treatment with black tea extract showed significant suppression of post-prandial blood glucose and obesity (p<0.05). The weight of the intestine of mice treated with black tea extract was significantly reduced (p<0.05). From these results, African black tea used in this study showed a suppressive effect on the elevation of blood glucose during food intake and the body weight.

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참고문헌

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