YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Synthesis of 6- Hydroxy-7 -methoxychroman-2-carboxylic Acid Dialkylaminoalkylamides

6-하이드록시-7-메톡시크로만-2-카복실산 디알킬아미노알킬아마이드 합성

  • Published : 2006.10.01
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Abstract

In the course of developing novel antioxidants, we synthesized four of 6-hydroxy-7-methoxy-4-oxochroman-2carboxylic acid dialkylamides (3a-d) $(13{\sim}18%)$ and four of 6-hydroxy-7-methoxychroman-2-carboxylic acid dialkylamides (4a-d) $(52{\sim}89%)$, incorporating the basic amine functionality. None of these compounds exhibited significant antioxidant activity possibly due to the hydrophilic character of the basic amine side chains.

Keywords

References

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