대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제27권1호
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- Pages.138-148
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- 2006
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- 1226-9174(pISSN)
인진청간탕(茵蔯淸肝湯)이 인체 간암세포의 혈관생성인자 발현에 미치는 영향
The Effects of Injinchunggan-tang(Yinchenqinggan-tang) on Expression of Angiogenic Factors in HepG2 Cells
- 김철우 (경희대학교 한의과대학 간계내과학교실) ;
- 김영철 (경희대학교 한의과대학 간계내과학교실) ;
- 이장훈 (경희대학교 한의과대학 간계내과학교실) ;
- 우홍정 (경희대학교 한의과대학 간계내과학교실)
- Kim, Chul-Woo (Department of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
- Kim, Young-Chul (Department of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
- Lee, Jang-Hoon (Department of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
- Woo, Hong-Jung (Department of Internal Medicine, College of Oriental Medicine, Kyung Hee University)
- 발행 : 2006.03.30
초록
Objectives: This study was designed to investigate the effects of Injinchunggan-tang(Yinchenqinggan-tang) on expression of angiogenic factors in HepG2 cells. Materials and Methods : The mRNA expression levels and protein secretion levels of angiogenic factors were measured using quantitative RT-PCR, Western blot and ELISA assay respectively in Injinchunggan-tang-treated and untreated HepG2 cells. Results : Injinchunggan-tang(Yinchenqinggan-tang) reduced mRNA expression levels and protein secretion levels of angiogenic factors, especially VEGF, bFGF and
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