The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Comparison and Analysis of Several Main Components between Hot Water Extract and Alcohol Extract of Gamichungsangbohatang

가미청상보하탕(加味淸上補下湯) 열수추출물(熱水抽出物)과 알코올추출물(抽出物)의 지표물질(指標物質) 및 패턴의 비교분석(比較分析)

  • Min, Jung-Ki (Division of Respiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Jung, Hee-Jae (Division of Respiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Rhee, Hyung-Koo (Division of Respiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Jung, Sung-Ki (Division of Respiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University)
  • 민정기 (경희대학교 한의과대학 폐계내과학 교실) ;
  • 정희재 (경희대학교 한의과대학 폐계내과학 교실) ;
  • 이형구 (경희대학교 한의과대학 폐계내과학 교실) ;
  • 정승기 (경희대학교 한의과대학 폐계내과학 교실)
  • Published : 2006.03.30
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Abstract

Objectives : To find out more pharmacologically efficient way of extraction of herbal dicoction, Gamichungsangbohatang (GMCSBHT). Methods : Several main components of GMCSBHT was compared and analysed between hot water extract of GMCSBHT and Alcohol(70% ethanol) extract of GMCSBHT via HPLC method. Results : Hot water extract of GMCSBHT showed relatively more component content than ethanol extract of GMCSBHT. Also weighted mean of main components of hot water extraction of GMCSBHT was higher than that of alcohol extract of GMCSBHT. But from chromatographic pattern analysis of matching ratio and similarity ratio showed that these two forms of extracts might have different chemical composition, and 3D PDA plot of alcohol extract of GMCSBHT showed high peaks near UV $190{\sim}220nm$ which was invisible in hot water extract of GMCSBHT. Conclusion : Alcohol extract of GMCSBHT may have some special components which do not exist in hot water extract of GMCSBHT.

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