Journal of Acupuncture Research
- Volume 23 Issue 3
- /
- Pages.37-45
- /
- 2006
- /
- 2586-288X(pISSN)
- /
- 2586-2898(eISSN)
Effect of Daekumeumja Herb-acupuncture on c-Fos Expression in Hippocampus of Alcohol Intoxicated Rats
대금음자 약침이 알코올 독성 흰쥐의 해마에서 c-Fos 발현에 미치는 영향
- Lee, Tae-Ho (Department of Acupuncture & Moxibustion, Oriental Medicine Hospital, Se-Myung University) ;
- Lee, Eun-Yong (Department of Acupuncture & Moxibustion, Oriental Medicine Hospital, Se-Myung University)
- Published : 2006.06.20
Abstract
Objectives : The study was conducted to investigate the effect of Deakumeumja herb-acupuncture on c-Fos expression in each area of the hippocampus of Alcohol intoxicated rats. Methods : Experimental groups were divided into five groups ; normal group, the alcohol-treated (control) group, the alcohol- 1 mg/kg Daekumeumja treated (sample A) group, the alcohol- 5 mg/kg Daekumeumja treated (sample B) group, the alcohol- 10 mg/kg Daekumeumja treated (sample C) group (n = 6 for each group). Rats of normal group were injected intraperitoneally with saline once a day for 5 consecutive days, while animals of the alcohol-treated (control) group were injected once a day with 2 g/kg of alcohol for the same duration of time. Animals of the alcohol and Daekumeumja-treated (sample A, B, C) groups were acupunctured at Chung-wan