Journal of Acupuncture Research
- 제23권2호
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- Pages.73-90
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- 2006
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- 2586-288X(pISSN)
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- 2586-2898(eISSN)
Protective Action of Cartilage and Bone Destruction by Deer Antler Herbal-acupuncture Solution, the Pilose Antler of Cervus Korean TEMMINCK Var. Mantchuricus Swinhoe, on Type II Collagen-induced Arthritis in Mice
- Kim, Joo-Kyung (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dongguk University) ;
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Lee, Seung-Deok
(Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dongguk University) ;
- Jeong, Yong-Rae (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dongguk University) ;
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Kim, Kap-Sung
(Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dongguk University)
- 발행 : 2006.04.20
초록
Objectives : The effects of water extract of deer antler herbal-acupunture solution(DHS), prepared from the pilose antler of Cervus korea TEMMINCK var. mantchuricus Swinhoe (Nokyong), a traditional immunosuppressive and immune-activating Korean herbal- acupuncture, on collagen-induced arthritis(CIA:RA model) in mice was studied. Destruction of cartilage and bone are hallmarks of human rheumatoid arthritis, and controlling these erosive processes is the most challenging objective in the treatment of RA. Methods : We investigated the tissue protective effects of deer antler treatment using established murine collagen-induced arthritis(CIA) as a model. Potential synergy of low dosages of anti-inflammatory glucocorticosteroids and deer antler was also evaluated. Results : Treatment of established murine CIA with deer antler herbal-acupunture solution(DHS)
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