The Korea Journal of Herbology (대한본초학회지)
- Volume 21 Issue 1
- /
- Pages.9-15
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- 2006
- /
- 1229-1765(pISSN)
- /
- 2288-7199(eISSN)
Effect of Lonicerae Flos-Skin on Contact Hypersensitivity induced by Repeat Elicitation of DNCB
금은화 화장수가 DNCB로 유발된 접촉성피부염에 미치는 영향
-
Kim, Sang-Chan
(College of Oriental Medicine, Daegu Haany University)
;
- Lee, Jae-Ryoung (College of Oriental Medicine, Daegu Haany University) ;
-
Choi, Kyung-Im
(Dept. of Beauty Coordination, Daegu Health College)
;
-
Park, Sook-Jahr
(College of Oriental Medicine, Daegu Haany University)
;
-
Kwon, Young-Kyu
(College of Oriental Medicine, Daegu Haany University)
;
-
Byun, Sung-Hui
(College of Oriental Medicine, Daegu Haany University)
-
김상찬
(대구한의대학교 한의과대학 한의학과)
;
- 이재령 (대구한의대학교 한의과대학 한의학과) ;
-
최경임
(대구보건대학 뷰티코디네이션과)
;
-
박숙자
(대구한의대학교 한의과대학 한의학과)
;
-
권영규
(대구한의대학교 한의과대학 한의학과)
;
-
변성희
(대구한의대학교 한의과대학 한의학과)
- Published : 2006.03.30
Abstract
Objectives : Lonicerae Flos has been known as a useful plant with anti-inflammatory, antioxidative and immunosuppressive activity. To evaluate anti-inflammatory effect of Lonicerae Flos, we treated Lonicerae Flos-skin in animal model system induced contact hypersensitivity. Methods : Contact hypersensitivity, a local inflammatory response of the skin, was induced by spreading the right ear of BALB/c mouse with 1% DNCB. Lonicerae Flos-skin was prepared by dissolving 1% water extract of Lonicerae Flos in skin vehicle and treated everyday for 2 weeks on the right ear. Results : Lonicerae Flos-skin significantly reduced a mouse ear thickness swelled by 1% of DNCB treatment compared with skin vehicle-treated control group. Lonicerae Flos-skin also reduced IgG and IgE in serum obtained from blood of 1% DNCB-treated mouse. Conclusion : These results showed that Lonicerae Flos-skin could be used as a pharmaceutical material with antiinflammatory effects by reducing IgG and IgE in contact hypersensitivity mouse model by DNCB.