References
- Elias AD. Small cell lung cancer: state-of-the-art therapy in 1996. Chest 1997;112:251S-8S https://doi.org/10.1378/chest.112.1.251
- Simon GR, Wagner H. Small cell lung cancer. Chest 2003;123:259S-71S https://doi.org/10.1378/chest.123.1_suppl.259S
- Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002;2:48-58 https://doi.org/10.1038/nrc706
- Chen CJ, Chin JE, Ueda K, Clark DP, Pastan I, Gottesman MM, et al. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 1986;47:381-9 https://doi.org/10.1016/0092-8674(86)90595-7
- Dean M, Rzhetsky A, Allikmets R. The human ATPbinding cassette (ABC) transporter superfamily. Genome Res 2001;11:1156-66 https://doi.org/10.1101/gr.GR-1649R
- Stouch TR, Gudmundsson O. Progress in under. standing the structure-activity relationships of Pglycoprotein. Adv Drug Deliv Rev 2002;54:315-28 https://doi.org/10.1016/S0169-409X(02)00006-6
- Holzmayer TA, Hilsenbeck S, von Hoff DD, Raninson IB. Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas. J Natl Cancer Inst 1992;84:1486-91 https://doi.org/10.1093/jnci/84.19.1486
- Poupon MF, Arvelo F, Goguel AF, Bourgeois Y, Jacrot M, Hanania N, et al. Response of small-cell lung cancer xenografts to chemotherapy: multidrug resistance and direct clinical correlates. J Natl Cancer Inst 1993;85:2023-9 https://doi.org/10.1093/jnci/85.24.2023
- Campling BG, Young LC, Baer KA, Lam YM, Deeley RG, Cole SP, et al. Expression of the MRP and MDR1 multidrug resistance genes in small cell lung cancer. Clin Cancer Res 1997;3:115-22
- Kawasaki M, Nakanishi Y, Kuwano K, Yatsunami J, Takayama K, Hara N. Immunohistochemically detected p53 and P-glycoprotein predict the response to chemotherapy in lung cancer. Eur J Cancer 1998; 34:1352-7 https://doi.org/10.1016/S0959-8049(98)00067-7
- Hsia TC, Lin CC, Wang JJ, Ho ST, Kao A. Re. lationship between chemotherapy response of small cell lung cancer and P-glycoprotein or multidrug resistance-related protein expression. Lung 2002;180: 173-9 https://doi.org/10.1007/s004080000091
- Lutterbach B, Sun D, Schuetz J, Hiebert SW. The MYND motif is required for repression of basal transcription from the multidrug resistance 1 pro. moter by the t(8;21) fusion protein. Mol Cell Biol 1998;18:3604-11 https://doi.org/10.1128/MCB.18.6.3604
- Nakayama M, Wada M, Harada T, Nagayama J, Kusaba H, Ohshima H, et al. Hypomethylation status of CpG sites at the promoter region and overexpression of the human MDR1 gene in acute myeloid leukemias. Blood 1998;92:4296-307
- Mickley LA, Spengler BA, Knutsen TA, Biedler JL, Fojo T. Gene rearrangement: a novel mechanism for MDR-1 gene activation. J Clin Invest 1997;99:1947- 57 https://doi.org/10.1172/JCI119362
- Marzolini C, Paus E, Buclin T, Kim RB. Polymor. phisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. Clin Pharmacol Ther 2004;75:13-33 https://doi.org/10.1016/j.clpt.2003.09.012
- Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmoller J, Johne A, et al. Functional polymor. phisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci U S A 2000;97:3473-8
- Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI, et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70:189-99 https://doi.org/10.1067/mcp.2001.117412
- Fromm MF. The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans. Adv Drug Deliv Rev 2002;54:1295-310 https://doi.org/10.1016/S0169-409X(02)00064-9
- World Health Organization. WHO handbook for reporting results of cancer treatment, WHO offset publication no. 48. Geneva: World Health Organization; 1979
- Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001;68:978-89 https://doi.org/10.1086/319501
- Tang K, Ngoi SM, Gwee PC, Chua JM, Lee EJ, Chong SS, et al. Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian po. pulations. Pharmacogenetics 2002;12:437-50 https://doi.org/10.1097/00008571-200208000-00004
- Kroetz DL, Pauli-Magnus C, Hodges LM, Huang CC, Kawamoto M, Johns SJ, et al. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics 2003;13:481-94 https://doi.org/10.1097/00008571-200308000-00006
-
Park SH, Lee GY, Jeon HS, Lee SJ, Kim KM, Jang SS, et al. -93G
$\rightarrow$ A polymorphism of hMLH1 and risk of primary lung cancer. Int J Cancer 2004;112: 678-82 https://doi.org/10.1002/ijc.20359 - Johne A, Kopke K, Gerloff T, Mai I, Rietbrock S, Meisel C, et al. Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene. Clin Pharmacol Ther 2002;72:584-94 https://doi.org/10.1067/mcp.2002.129196
- Gerloff T, Schaefer M, Johne A, Oselin K, Meisel C, Cascorbi I, et al. MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males. Br J Clin Pharmacol 2002;54:610-6 https://doi.org/10.1046/j.1365-2125.2002.01691.x
- Nakamura T, Sakaeda T, Horinouchi M, Tamura T, Aoyama N, Shirakawa T, et al. Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects. Clin Pharmacol Ther 2002;71:297-303 https://doi.org/10.1067/mcp.2002.122055
- Illmer T, Schuler US, Thiede C, Schwarz UI, Kim RB, Gotthard S, et al. MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res 2002;62:4955-62
- Tanabe M, Ieiri I, Nagata N, Inoue K, Ito S, Kanamori Y, et al. Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J Pharmacol Exp Ther 2001;297:1137-43
- Siegsmund M, Brinkmann U, Schaffeler E, Weirich G, Schwab M, Eichelbaum M, et al. Association of the P-glycoprotein transporter MDR1(C3435T) poly. morphism with the susceptibility to renal epithelial tumors. J Am Soc Nephrol 2002;13:1847-54 https://doi.org/10.1097/01.ASN.0000019412.87412.BC
- Drozdzik M, Bialecka M, Mysliwiec K, Honczarenko K, Stankiewicz J, Sych Z. Polymorphism in the Pglycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease. Pharmacogenetics 2003;13:259-63 https://doi.org/10.1097/00008571-200305000-00004