Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Smoking Induced Acute Eosinophilic Pneumonia

흡연에 의한 급성 호산구성 폐렴 1예

  • Jo, Hyun Chul (Departments of Internal Medicine, KyungHee University of Medicine) ;
  • Lee, Young Joo (Departments of Internal Medicine, KyungHee University of Medicine) ;
  • Park, Myung Jae (Departments of Internal Medicine, KyungHee University of Medicine) ;
  • Kang, Hong Mo (Departments of Internal Medicine, KyungHee University of Medicine) ;
  • You, Jee Hong (Departments of Internal Medicine, KyungHee University of Medicine)
  • 조현철 (경희대학교 의과대학 내과학교실) ;
  • 이영주 (경희대학교 의과대학 내과학교실) ;
  • 박명재 (경희대학교 의과대학 내과학교실) ;
  • 강홍모 (경희대학교 의과대학 내과학교실) ;
  • 유지홍 (경희대학교 의과대학 내과학교실)
  • Received : 2005.02.21
  • Accepted : 2005.05.20
  • Published : 2005.05.30
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Abstract

Acute eosinophilic pneumonia (AEP) has been described as an idiopathic febrile illness with a duration of less than seven days with severe hypoxemia, pulmonary infiltrates, and no history of asthma. It has been reported that AEP is associated with smoking. Although the pathogenesis of smoking induced AEP is being actively studied, there is no direct histological evidence that smoking actually induces AEP. Recently, we encountered a case of AEP that may have been caused by smoking. We performed a cigarette smoking challenge test to verify that smoking was indeed the cause of AEP in this patient. Smoking induced an increase the proportion of eosinophils in the bronchoalveolar lavage fluid without any respiratory symptoms or abnormal radiological findings. This result suggests that smoking was the cause of AEP in this patient.

최근 일본 연구자들을 중심으로 새로 시작한 흡연에 의해 발생한 급성 호산구성 폐렴의 증례 보고가 증가하고 있고 또 발병기전에 대한 연구도 점차 증가하고 있는 추세이다. 본 저자들도 흡연에 의해 발생한 급성 호산구성 페렴환자를 경험하고 이 환자에서 흡연유발검사를 통해 새로 시작한 흡연이 급성 호산구성폐렴의 원인임을 확인하여 이 환자의 임상적인 특징과 경과를 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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