Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Primary Mucosa-Associated Lymphoid Tissue Lymphoma of the Trachea and Colon

기관과 대장에 발생한 원발성 mucosa-associated lymphoid tissue 림프종 1예

  • Bae, Jun Yong (Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Na, Hyun Sik (Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Choi, Jae Sung (Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Choi, Jun Ho (Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Park, Sung Gyu (Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Jang, An Soo (Department of Internal Medicine, Soonchunhyang University, School of Medicine) ;
  • Ko, Eun Suk (Department of Anatomical Pathology, Soonchunhyang University, School of Medicine) ;
  • Paik, Sang Hyun (Department of Diagnostic Radiology, Soonchunhyang University, School of Medicine) ;
  • Park, Jae Sung (Department of Diagnostic Radiology, Soonchunhyang University, School of Medicine) ;
  • Park, Choon Sik (Department of Internal Medicine, Soonchunhyang University, School of Medicine)
  • 배준용 (순천향대학교 의과대학 내과학교실) ;
  • 나현식 (순천향대학교 의과대학 내과학교실) ;
  • 최재성 (순천향대학교 의과대학 내과학교실) ;
  • 최준호 (순천향대학교 의과대학 내과학교실) ;
  • 박성규 (순천향대학교 의과대학 내과학교실) ;
  • 장안수 (순천향대학교 의과대학 내과학교실) ;
  • 고은석 (순천향대학교 의과대학 해부병리학교실) ;
  • 백상현 (순천향대학교 의과대학 진단방사선과교실) ;
  • 박재성 (순천향대학교 의과대학 진단방사선과교실) ;
  • 박춘식 (순천향대학교 의과대학 내과학교실)
  • Received : 2005.06.16
  • Accepted : 2005.07.12
  • Published : 2005.08.30
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Abstract

The 64-year-old female patient with cough and intermittent hemoptysis of six months duration visited our hospital. On chest computed tomography, a small, ovoid, 1.3cm sized and well enhanced lesion was detected on the distal trachea. Two multiple lobulated lesions on the sigmoid and transverse colon were revealed on the colonoscopy. The histological findings showed small and medium sized lymphocytes infiltration, CD20 and CD79a positive staining and multiple lymphoepithelial lesions on the distal trachea and colon tissues. Herein, a case of primary MALT lymphoma, with involvement of the trachea and colon, which was treated with rituximab (CD20 anti-monoclonal antibody), cyclophosphamide, adriamycin, vincristine and prednisolone (CHOP regimen), is reported.

MALT 림프종은 안구, 침샘, 감상선, 폐, 위, 소장, 대장, 방광, 여성 생식기에 발생하며, 대부분이 단일기관을 침범하고 국소 치료와 화학요법에 좋은 예후를 보인다. MALT 림프종이 기관을 침범하는 경우는 거의 보고된 경우가 없으며 국내에선 폐의 MALT 림프종이 보고된 적이 있었다. 이에 저자 등은 기관과 대장에 발생한 원발성 MALT 림프종 1예를 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

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