Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Two Cases of Bronchiolitis Obliterans Organizing Pneumonia treated with Steroid and Cyclosporine therapy

스테로이드와 Cyclosporine으로 치료한 폐쇄성세기관지염기질화폐렴 2예

  • Lee, Jong Hoo (Departments of Internal Medicine, Kyung Hee University College of Medicine) ;
  • Park, Myung Jae (Departments of Internal Medicine, Kyung Hee University College of Medicine) ;
  • Kim, Yi Hyung (Departments of Internal Medicine, Kyung Hee University College of Medicine) ;
  • Park, Byung Jo (Departments of Internal Medicine, Kyung Hee University College of Medicine) ;
  • Oh, Won Taek (Departments of Internal Medicine, Kyung Hee University College of Medicine) ;
  • Lee, Myung Yeol (Departments of Internal Medicine, Kyung Hee University College of Medicine) ;
  • Yoo, Jee Hong (Departments of Internal Medicine, Kyung Hee University College of Medicine) ;
  • Kang, Hong Mo (Departments of Internal Medicine, Kyung Hee University College of Medicine)
  • 이종후 (경희대학교 의과대학 내과학교실) ;
  • 박명재 (경희대학교 의과대학 내과학교실) ;
  • 김이형 (경희대학교 의과대학 내과학교실) ;
  • 박병조 (경희대학교 의과대학 내과학교실) ;
  • 오원택 (경희대학교 의과대학 내과학교실) ;
  • 이명렬 (경희대학교 의과대학 내과학교실) ;
  • 유지홍 (경희대학교 의과대학 내과학교실) ;
  • 강홍모 (경희대학교 의과대학 내과학교실)
  • Received : 2005.06.28
  • Accepted : 2005.08.17
  • Published : 2005.09.30
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Abstract

A rapid response to corticosteroid treatment and a generally favourable outcome are characteristic features of BOOP (Bronchiolitis obliterans organizing pneumonia). However, with increasing experience of the clinical spectrum of this disease, it is now recognized that some patients are refractory to steroid, which is associated with a poor prognosis. Here, two cases of BOOP initially treated with predinisone and antibiotics without effects, but subsequently responded to secondary cyclosporine treatment, are reported.

폐쇄성세기관지염기질화폐렴은 스테로이드에 반응을 매우 잘하는 질환으로 알려져 있지만, 본 두 증례에서는 충분한 용량의 스테로이드에 반응을 보이지 않고 이차적 약제인 cyclosporine에 의해 임상적, 방사선학적 호전을 보여 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

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