Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Bronchiolitis Obliterans Organizing Pneumonia Following CHOP Chemotherapy and Filgrastim Use in a Patient with Diffuse Large B-cell Lymphoma

미만성 거대 B형 세포 림프종 환자에서 CHOP 항암 치료와 Filgrastim 투여 후 발생한 폐쇄세기관지기질화폐렴 1례

  • Chung, Wou Young (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Byun, Min Kwang (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Lee, Jin Hyoung (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Hahn, Chang Hoon (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kang, Shin Myung (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Jin Seok (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Cho, San Ho (Department of Pathology, Yonsei University College of Medicine) ;
  • Kim, Young Sam (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Se Kyu (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Chang, Joon (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Sung Kyu (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Moo Suk (Department of Internal Medicine, Yonsei University College of Medicine)
  • 정우영 (연세대학교 의과대학 내과학교실) ;
  • 변민광 (연세대학교 의과대학 내과학교실) ;
  • 이진형 (연세대학교 의과대학 내과학교실) ;
  • 한창훈 (연세대학교 의과대학 내과학교실) ;
  • 강신명 (연세대학교 의과대학 내과학교실) ;
  • 김진석 (연세대학교 의과대학 내과학교실) ;
  • 조상호 (연세대학교 의과대학 병리학교실) ;
  • 김영삼 (연세대학교 의과대학 내과학교실) ;
  • 김세규 (연세대학교 의과대학 내과학교실) ;
  • 장준 (연세대학교 의과대학 내과학교실) ;
  • 김성규 (연세대학교 의과대학 내과학교실) ;
  • 박무석 (연세대학교 의과대학 내과학교실)
  • Received : 2005.10.12
  • Accepted : 2005.10.28
  • Published : 2005.11.30
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Abstract

Bronchiolitis obliterans organizing pneumonia (BOOP) is often diagnosed in patients with pneumonia who respond poorly to antibiotics. BOOP is often idiopathic, and the etiology of the remaining cases has been attributed to a wide range of agents or medical conditions. When a patient develops the clinical symptoms characteristic of BOOP, the medical team must endeavor to determine the etiology of this disease because it can be treated with glucocorticoid and avoidance of the causative agent. In particular, if BOOP is diagnosed during or after chemotherapy for a malignancy, the possible culprit agent can be the anti cancer drugs but other drugs used for supportive care must be also be considered. We report a case of BOOP that arose after CHOP chemotherapy and a filgrastim injection in a patient with a diffuse large B-cell lymphoma.

Keywords

References

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