소세포성 폐암과 연관된 망막증 1예

A Case of Cancer Associated Retinopathy with Small Cell Lung Carcinoma

  • 임성민 (예수병원 호흡기 내과) ;
  • 배종오 (예수병원 호흡기 내과) ;
  • 조상건 (예수병원 호흡기 내과) ;
  • 강상구 (예수병원 호흡기 내과) ;
  • 이은영 (예수병원 호흡기 내과) ;
  • 김성국 (전북대학교 의과대학 내과학교실) ;
  • 김영 (예수병원 호흡기 내과) ;
  • 곽진영 (예수병원 호흡기 내과) ;
  • 김귀완 (김귀완 내과)
  • Lim, Seongmin (Department of Internal medicine, Presbyterian Medical Center) ;
  • Bae, Jongoh (Department of Internal medicine, Presbyterian Medical Center) ;
  • Cho, Sanggeon (Department of Internal medicine, Presbyterian Medical Center) ;
  • Kang, Sanggu (Department of Internal medicine, Presbyterian Medical Center) ;
  • Lee, Eunyoung (Department of Internal medicine, Presbyterian Medical Center) ;
  • Kim, Sungkuk (Department of Internal medicine, Chonbuk National University Medical School) ;
  • Kim, Young (Department of Internal medicine, Presbyterian Medical Center) ;
  • Kwak, Jinyoung (Department of Internal medicine, Presbyterian Medical Center) ;
  • Kim, Kwiwan (Kim kwiwan Medical Clinic)
  • 투고 : 2005.10.04
  • 심사 : 2005.10.24
  • 발행 : 2005.12.30

초록

저자들은 시야 결손 등의 시력 변화를 주 증상으로 내원한 환자에서 소세포 폐암과 이로 인한 부종양성증후군으로 동반된 암 관련 망막증을 진단하고 항암화학요법을 시행하여, 원발 병변의 부분 관해 보였으나, 시야 결손은 회복되지 않았던 1예를 경험하였기에 문헌 고찰과 함께 보고 하는 바이다.

Cancer associated retinopathy (CAR) syndrome is a very rare ocular manifestation of paraneoplastic syndrome, and is characterized clinically by progressive visual impairment. Immune cross-reactivity between antigens in the cancerous tissue and antigens in the retina may play an important role in its pathogenesis, and most of cases are associated with lung carcinoma, particularly small cell lung cancer. The clinical triad of CAR is described as photosensitivity, ring scotomata, and an attenuated retinal arterial caliber. Here, we report a 61-year old male patient with CAR syndrome, who had small cell lung carcinoma in the stage of limited disease, with a brief review of the relevant literature.

키워드

참고문헌

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