A Case of Gastric Outlet Obstruction Complicated by Peptic Ulcer Secondary to Non-Steroidal Anti-Inflammatory Drug (NSAID)

진통소염제에 의한 위 십이지장 궤양에 합병된 위 출구 폐쇄 1예

  • Choi, Chang Hwan (Department of Pediatrics, Bundang Jesaeng General Hospital) ;
  • Byun, Sung Hwan (Department of Pediatrics, Bundang Jesaeng General Hospital) ;
  • Chang, Soo Hee (Department of Pediatrics, Bundang Jesaeng General Hospital) ;
  • Paik, So Ya (Department of Pathology, Bundang Jesaeng General Hospital)
  • Received : 2005.07.20
  • Accepted : 2005.08.30
  • Published : 2005.09.01

Abstract

Peptic ulcer disease complicated with gastric outlet obstruction is rare in children. Even though NSAIDs have been reported to cause various adverse events, they are still regarded as safe and, therefore, widely utilized in children. In the past, pediatric patients who were at risk of seizure due to high fever, were treated with dipyrone (Metamizole sodium) injection which inhibits cyclooxygenase-1 and inhibit prostaglandin, to weaken the gastro-duodenal defensive mechanism. A case of an infant with multiple esophagogatroduodenal ulcers and bleeding caused by NSAID complicated with gastric outlet obstruction is reported in this paper.

저자들은 11개월 영아의 고열을 조절하기 위해 진통소염제 근주와 경구 해열제 병용투여 후 발생한 다발성 식도 위 십이지장 궤양 치료 과정 중 조기에 위 출구 폐쇄가 합병된 1예를 경험하였기에 보고하는 바이다.

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