Amyotrophic Lateral Sclerosis Combined with Abnormal Sensory Nerve Conduction

감각신경전도 이상을 동반한 근위축성측색경화증

  • Seo, Sang Hyuk (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Hanmaeum General Hospital) ;
  • An, Jae Young (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Hanmaeum General Hospital) ;
  • Lee, Taek-Jun (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Hanmaeum General Hospital) ;
  • Suh, Yeon-Lim (Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Hanmaeum General Hospital) ;
  • Shin, Kyong Jin (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Hanmaeum General Hospital) ;
  • Kim, Byoung Joon (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Hanmaeum General Hospital)
  • 서상혁 (성균관대학교 의과대학 삼성서울병원 신경과학교실) ;
  • 안재영 (성균관대학교 의과대학 삼성서울병원 신경과학교실) ;
  • 이택준 (성균관대학교 의과대학 삼성서울병원 신경과학교실) ;
  • 서연림 (성균관대학교 의과대학 삼성서울병원 진단병리과학교실) ;
  • 신경진 (성균관대학교 의과대학 삼성서울병원 신경과학교실) ;
  • 김병준 (성균관대학교 의과대학 삼성서울병원 신경과학교실)
  • Published : 2005.12.30

Abstract

Underlying neuropathies combined with amyotrophic lateral sclerosis (ALS) cast doubt on the diagnosis of ALS when present. Abnormal sural nerve conductions were found in 3 patients with clinically definite ALS. Pathologically demyelinating, axonal, or vasculitic neuropathy was suggested respectively. High dose oral corticosteroid had no effect and clinical courses were deteriorating in all the patients. The causes of combined neuropathies were unclear. Possibility of direct consequence of ALS, concomitant neuropathies, or rare variants of ALS should be considered in these cases.

Keywords