Journal of Yeungnam Medical Science
- 제22권2호
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- Pages.253-258
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- 2005
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- 2799-8010(eISSN)
전신성 홍반성 루푸스에서 고용량 경정맥 당질코르티코이드로 치료된 단백질 소실성 장질환 1예
A Case of Protein-losing Enteropathy Treated with High Dose Intravenous Glucocorticoid Therapy in Systemic Lupus Erythematosus
- 이규형 (영남대학교 의과대학 내과학교실) ;
- 권창모 (영남대학교 의과대학 내과학교실) ;
- 김현도 (영남대학교 의과대학 내과학교실) ;
- 윤대영 (영남대학교 의과대학 내과학교실) ;
- 이재웅 (영남대학교 의과대학 내과학교실) ;
- 홍영훈 (영남대학교 의과대학 내과학교실) ;
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이충기
(영남대학교 의과대학 내과학교실)
- Lee, Kyu-Hyung (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) ;
- Kwon, Chang-Mo (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) ;
- Kim, Hyun-Do (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) ;
- Yun, Dae-Young (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) ;
- Lee, Jae-Yoong (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) ;
- Hong, Yeong-Hoon (Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University) ;
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Lee, Choong-Ki
(Division of Rheumatology, Department of Internal Medicine, College of Medicine, Yeungnam University)
- 발행 : 2005.12.30
초록
Generalized edema and hypoalbuminemia are relatively common presenting manifestations in many clinical situations. The differential diagnosis of hypoalbuminemia include: Kwashiorkor, synthetic dysfunction of the liver, and excessive protein loss as in nephrotic syndrome. In systemic lupus erythematosus (SLE), hypoalbuminemia and generalized edema are most commonly due to protein loss associated with lupus nephritis; gastrointestinal involvement is uncommon, and therefore protein loss through the gastrointestinal tract is quite rare. We report a case of a protein losing enteropathy (PLE) associated with SLE. The patient was referred to our hospital for generalized edema, arthralgia and facial rash. After clinical evaluation, the patient met the criteria for the SLE diagnosis; hypoalbuminemia with general edema was consistent with a protein losing enteropathy. After two weeks of therapy with parenteral high dose glucocorticoid, the patients was improved in laboratory findings as well as clinical symptoms.