Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)
- Volume 37 Issue 2
- /
- Pages.129-137
- /
- 2005
- /
- 1738-3544(pISSN)
- /
- 2288-1662(eISSN)
Anti-Obesitic Effect of Mulberry Root-Bark (Mori radicis Cortex) in Zucker Rats with High Lipid Diet Induced-Obesity
고지방식이에 의해 비만이 유도된 Zucker Rats에서 상백피분말의 비만 개선효과
- Hong, Seong-Hee (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
-
Kim, Dong-Kyu
(College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University)
;
- Lee, Nam-Jin (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
- Cho, Jung-Hee (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
-
Kang, Jong-Koo
(College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University)
;
-
Kim, Yun-Bae
(College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University)
;
- Park, Jung-Hui (Park, Jung-Hui Oriental Medical Clinic) ;
-
Hwang, Seock-Yeon
(Department of Clinical Laboratory Medicine, Chungbuk National University Hospital)
- 홍성희 (충북대학교 수의과대학) ;
-
김동규
(충북대학교 수의과대학)
;
- 이남진 (충북대학교 수의과대학) ;
- 조정희 (충북대학교 수의과대학) ;
-
강종구
(충북대학교 수의과대학)
;
-
김윤배
(충북대학교 수의과대학)
;
- 박정휘 (박정휘 한의원) ;
-
황석연
(충북대학교병원 진단검사의학과)
- Published : 2005.08.31
Abstract
This study was performed to investigate the anti-obesitic effect of mulberry root-bark on male and female Zucker FA/FA or FA/fa rats. Obesity in the rats was induced by feeding high-lipid diet contained 3% corn oil and 1% cholesterol. Experimental groups in male and female rats were assigned to normal diet group (normal control), high-lipid diet group(positive control) and 3% mulberry root-bark powder in high-lipid diet group (MRC). The mulberry treated-group showed decreases of body weight, FER (food efficiency ratio) value and lipid peroxidation in the liver and increase of high density lipoprotein cholesterol (HDL-C) value, compared with positive control groups. Our findings suggest that mulberry root-bark has a potential role in preventing or improving obesity from the following points of view, body weight, serum lipids and antioxidant enzyme activities.