Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

Osteoblast adhesion and differentiation on magnesium titanate surface

마그네슘 티타네이트 표면의 조골세포 부착도와 분화

  • Choi, Seung-Min (Department of Periodontics, College of Dentistry, Kangnung National University) ;
  • Lee, Jae-Kwan (Department of Periodontics, College of Dentistry, Kangnung National University) ;
  • Ko, Sung-Hee (Department of Phamacology, College of Dentistry, Kangnung National University) ;
  • Um, Heung-Sik (Department of Periodontics, College of Dentistry, Kangnung National University) ;
  • Chang, Beom-Seok (Department of Periodontics, College of Dentistry, Kangnung National University)
  • 최승민 (강릉대학교 치과대학 치주과학교실) ;
  • 이재관 (강릉대학교 치과대학 치주과학교실) ;
  • 고성희 (강릉대학교 치과대학 약리학교실) ;
  • 엄흥식 (강릉대학교 치과대학 치주과학교실) ;
  • 장범석 (강릉대학교 치과대학 치주과학교실)
  • Published : 2005.12.31
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Abstract

The nature of the implant surface can directly influence cellular response, ultimately affecting the rate and quality of new bone tissue formation. The aim of this in vitro study was to investigate if human osteoblast-like cells, Saos-2, would respond differently when plated on disks of magnesium titanate and machined titanium. Magnesium titanate disks were prepared using Micro Arc Oxidation(MAO) methods. Control samples were machined commercially pure titanium disks. The cell adhesion, proliferation and differentiation were evaluated by measuring cell number, and alkaline phosphatase(ALPase) activity at 1 day and 6 day after plating on the titanium disks. Measurement of cell number and ALPase activity in Saos-2 cells at 1 day did not demonstrate any difference between machined titanium and magnesium titanate. When compared to machined titanium disks, the number of cells was reduced on the magnesium titanate disks at 6 day, while ALPase activity was more pronounced on the magnesium titanate. Enhanced differentiation of cells grown on magnesium titanate samples was indicated by decreased cell proliferation and increased ALPase activity.

Keywords

References

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