Submandibular Soft Tissue Actinomycosis Diagnosed by Fine Needle Aspiration Cytology - A Case Report -

세침흡인 세포검사로 진단된 턱밑 연조직 방선균증 - 1예 보고 -

  • Lee, Ho-Jung (Department of Pathology, Eulji Hospital, Eulji University School of Medicine) ;
  • Kim, Dong-Hoon (Department of Pathology, Eulji Hospital, Eulji University School of Medicine) ;
  • Lee, Won-Mi (Department of Pathology, Eulji Hospital, Eulji University School of Medicine) ;
  • Kim, Eun-Kyung (Department of Pathology, Eulji Hospital, Eulji University School of Medicine) ;
  • Joo, Jong-Eun (Department of Pathology, Eulji Hospital, Eulji University School of Medicine)
  • 이호정 (을지대학교 의과대학 을지병원 병리과) ;
  • 김동훈 (을지대학교 의과대학 을지병원 병리과) ;
  • 이원미 (을지대학교 의과대학 을지병원 병리과) ;
  • 김은경 (을지대학교 의과대학 을지병원 병리과) ;
  • 주종은 (을지대학교 의과대학 을지병원 병리과)
  • Published : 2005.05.31

Abstract

A patient with actinomyces infection of the submandibular soft tissue was diagnosed by fine needle aspiration cytology (FNAC). A 38-year-old woman presented with a right submandibular mass which slowly grew in size over one month. Clinically and radiologically, the lesion was considered as tuberculous lymphadenitis or cellulitis. The polymerase chain reaction for tuberculosis was done by aspirated specimen but the result was negative. The smears of aspiration cytology showed characteristic colonies (sulfur granules) of actinomyces in inflammatory background. After antibiotic therapy for eight months, the patient has been well, showing no detectable mass. This patient was simply and rapidly diagnosed by FNAC and can avoid unnecessary surgical biopsy.

References

  1. Russo TA. Agents of actinomycosis. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 5th ed. Philadelphia: Churchill Livingston, 2000;2645-54
  2. Pulverer G, Schutt-Gerowitt H, Schaal KP. Human cervicofacial actinomycoses: microbiological data for 1997 cases. Clin Infect Dis 2003;37:490-7 https://doi.org/10.1086/376621
  3. Varghese BT, Sebastian P, Ramachandran K, Pandey M. Actinomycosis of the parotid masquerading as malignant neoplasm. BMC Cancer 2004;4:7 https://doi.org/10.1186/1471-2407-4-7
  4. 김대중, 진소영, 이동화. 골반방선균증 -1예 보고- 대한세포병리학회지 1991;2:172-8
  5. 하창원, 고재수, 조경자, 장자준 세침흡인 세포학적 검사로 진단된 간 방선균증 -1예 보고- 대한세포병리학회지 1992;3: 100-3
  6. 이혜영, 염정숙, 최명범, 서지현, 임재영, 박찬후 등 제 4 새기형 누공이 있는 환아에서 생긴 갑상선 방선균증 1 례. 소아과 2004;47:696-700
  7. 홍석준, 주준범, 김용재, 이봉재 두경부에 발생한 방선균 증 3례 대한이비인후과학회지 2000;43: 1159-62
  8. Regezi JA, Sciubba J. Oral Pathology. 2nd ed Philadelphia: W.B.Saunders Co, 1993;45-6
  9. Neville BW, Damm DD, Allen CM, Bouqout JE. Oral and Maxillofacial Pathology. Philadelphia: W.B. Saunders Co, 1995;156-7
  10. deB Norman JE, Mitchell RD. Unusual condition of the major and minor salivary glands. Int J Oral Maxillofac Surg 1998;27; 157-72 https://doi.org/10.1016/S0901-5027(98)80003-9
  11. 박범정, 김태형, 김정현, 한동의. 이하선에 발생한 방선균 증 1례. 대한이비인후과학회지 2004;47:486-9
  12. 이진호, 박인우, 최항문, 허만석, 이삼선. 악하선에 발생 한 방선균증. 대한구강악안면방사선학회지. 2000;30: 132-7
  13. 서영진, 정헌, 진현민, 등. 갑상선종으로 오인된 경부 임파선 만성 방선균증. 대한외과학회지 2002;62:442-5
  14. Bubbico L, Caratozzolo M, Nardi F, Ruoppolo G, Greco A, Venditti M. Actinomycosis of submandibular gland: an unusual presentation. Acta Otorhinolaryngol Ital 2004;24: 37-9
  15. Das DK, Bhatt NC, Khan VA, Luthra UK. Cervicofacial actinomycosis: diagnosis by fine needle aspiration cytology. Acta Cytol 1989;33:278-80
  16. Gerbino G, Bernardi M, Secco F, Sapino A, Pacchioni D. Actinomycosis of the tongue. Report of two cases and review of the literature. Minerva Stomatol 1998;47:95-101
  17. Sudhakar SS, Ross JJ. Short-term treatment of actinomycosis: two cases and a review. Clin Infect Dis 2004;38:444-7 https://doi.org/10.1086/381099