Ultrastructure of the Submandibular Gland in the Lesser White-Toothed Shrew, Crocidura suaveolens

작은땃쥐 Crocidura suaveolens 악하선의 미세구조

  • Jeong, Soon-Jeong (Department of Oral Histology, College of Dentistry, Chosun University) ;
  • Jeong, Moon-Jin (Department of Oral Histology, College of Dentistry, Chosun University) ;
  • Kim, Do-Kyung (Department of Oral Physiology, College of Dentistry, Chosun University) ;
  • Kook, Joong-Ki (Department of Oral Biochemistry, College of Dentistry, Chosun University) ;
  • Kim, Heung-Joong (Department of Oral Anatomy, College of Dentistry, Chosun University) ;
  • Yoon, Myung-Hee (Division of Natural Sciences, College of Sciences, Kyungsung University) ;
  • Park, Joo-Cheol (Department of Oral Histology, College of Dentistry, Chosun University)
  • 정순정 (조선대학교 치과대학 구강조직학교실) ;
  • 정문진 (조선대학교 치과대학 구강조직학교실) ;
  • 김도경 (조선대학교 치과대학 구강생리학교실) ;
  • 국중기 (조선대학교 치과대학 구강생화학교실) ;
  • 김흥중 (조선대학교 치과대학 구강해부학교실) ;
  • 윤명희 (경성대학교 자연과학대학 자연과학부) ;
  • 박주철 (조선대학교 치과대학 구강조직학교실)
  • Published : 2005.06.01


The ultrastructure of submandibular gland was examined in the lesser white-toothed shrew, Crocidura suaveolens. The submandibular gland of C. suaveolens was a mixed gland composed of serous and mucous acinar cells. Secretory granules from the acini were discharged through the salivary ducts into the oral cavity. Serous and mucous acinar cells had well developed rough endoplasmic reticulum and mitochondria and large amount of granules. In case of serous acinar granules, an immature granule was formless and had only dense specks, and a matured granule was a complete round type delimiting by a single membrane and had a homogeneous dense center with dense specks on the border. In case of mucous acinar granules, while an immature granule was a round type and had an only homogeneous matrix and an indistinct limiting membrane, a mature granule was an even round type having a variety of pattern with several dense bands into the homogeneous matrix and had a distinct membrane. Therefore, a mature mucous acinar granule of C. suaveolens was not only distinct from those of the other mammalian species to have a variety of pattern but also from those of C. lasiura to have an even round type. A great serous-like secretory granules and Myelin-like body were observed in the cytoplasm and lumen of granular duct cells. Myelin-like body, a characteristic structure only reported in salivary gland of three shrews, was discharged from secretory cell into lumen by the manner of exocytosis which has little differences from discharging manner of secretory granules.

악하선의 미세구조를 작은땃쥐 Crocidura suaveolens에서 연구하였다. 작은땃쥐의 악하선은 장액선세포와 점액선세포로 구성된 혼합샘이었다. 이 샘포에서 분비된 과립들은 도관을 거쳐 구강으로 분비되었다. 장액선세포와 점액선세포는 잘 발달된 조면소포체와 미토콘드리아 그리고 많은 분비과립을 가지고 있었다. 장액선 분비과립의 경우, 미성숙 분비과립은 무형이면서 전자밀도가 있는 작은 알갱이로만 구성되었고, 성숙 과립은 단일막으로 싸여진 완전한 원형으로 전자밀도가 있는 균질의 중앙부와 전자밀도가 있는 작은 알갱이로 구성된 주변부를 가지고 있었다. 점액선 분비과립의 경우, 미성숙 과립은 원형으로 균질한 기질과 불명확한 경계막을 가지는 반면, 성숙 과립은 균질한 기질 내에 몇 개의 전자밀도가 있는 띠를 가짐으로서 문양의 다양성 가지는 매끈한 원형이었고 명확한 경계막을 가지고 있었다. 즉 작은 땃쥐의 성숙 점액선 분비과립은 문양의 다양성을 가져 다른 포유류와 구분될 뿐만 아니라 매끈한 원형이어서 C. lasiura의 그것과도 구분되었다. 거대한 분비 과립과 미엘린소체가 과립관세포의 세포질과 내강에서 관찰되었다. 3종의 땃쥐류 침샘의 과립관에서 만 보고된 특징적 구조물인 미엘린소체는 분비세포에서 내강으로 분비되었으며 분비과립의 배출방식과 약간의 차이점을 가졌다.



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