The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)
- Volume 18 Issue 3
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- Pages.92-109
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- 2005
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- 1229-4292(pISSN)
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- 2508-3619(eISSN)
The Anti-inflammatory Effect of Cheongyeolhawlhyeoltanggagyehyeoldeung (CYHHT) in cultured RAW264.7 cells and murine models of inflammation
RAW264.7세포주와 염증생쥐모델에서 항염증(抗炎症) 작용(作用)에 대한 청열활혈탕가계혈등(淸熱活血湯加鷄血藤)의 효과(效果)
- Han, Choong-Hee (Dept. of Ob & Gyn, College of Oriental Medicine, Daejeon Univ.) ;
- Yoo, Dong-Youl (Dept. of Ob & Gyn, College of Oriental Medicine, Daejeon Univ.)
- Published : 2005.08.31
Abstract
Purpose : The Purpose of this research was to investigate the effects of Cheongyeolhawlhyeoltanggagyehyeoldeung (CYHHT) on anti-inflammatory effects. Methods : As for the parameters of inflammation, levels of several inflammatory cytokines and chemical mediators were determined in mouse lung fibroblast cells(mLFC) and RAW264.7 cells. Also, changes in pathological features by drug treatment were investigated in the in vivo edema-induced rats by carrageenin /arachidonic acid or in the colitis-induced mice by DSS treatment. Results : The cytotoxicity of CYHHT on mLFC and RAW264.7 cells was not observed at 100, 50, 10, and