대한한방부인과학회지 (The Journal of Korean Obstetrics and Gynecology)
- 제18권4호
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- Pages.36-53
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- 2005
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- 1229-4292(pISSN)
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- 2508-3619(eISSN)
RAW264.7세포주와 염증생쥐모델에서 항염증(抗炎症) 작용(作用)에 대한 행경홍화탕(行經紅花湯)의 효과(效果)
Anti-inflammatory Effect of Haingkyunghonghwatang in cultured RAW264.7 cells and murine models of inflammation
- Min, Byung-Ho (Dept. of Ob & Gyn, College of Oriental Medicine, Daejeon Univ.) ;
- Yoo, Dong-Youl (Dept. of Ob & Gyn, College of Oriental Medicine, Daejeon Univ.)
- 발행 : 2005.11.30
초록
Purpose : The Purpose of this research was to investigate the effects of Haingkyunghonghwatang (HKHHT) on anti-inflammatory effects. Methods : As for the parameters of inflammation, levels of several inflammatory cytokines and chemical mediators were determined in mouse lung fibroblast cells(mLFC) and RAW264.7 cells. Also, changes in pathological features by drug treatment were investigated in the in vivo edema-induced rats by carrageenin/arachidonic acid or in the colitis-induced mice by DSS treatment. Results : The cytotoxicity of HKHHT on mLFC and RAW264.7 cells wasn't observed at 100, 50, 10, and