Genomics & Informatics
- 제3권4호
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- Pages.142-148
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- 2005
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- 1598-866X(pISSN)
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- 2234-0742(eISSN)
Comparative Genomics Study of Interferon-$\alpha$ Receptor-1 in Humans and Chimpanzees
- Kim, Il-Chul (Genome Structure Research Laboratory) ;
- Chi, Seung-Wook (Protein Analysis and Design Laboratory, Korea Research Institute of Bioscience and Biotechnology) ;
- Kim, Dae-Won (Genome Structure Research Laboratory, University of Science and Technology (UST)) ;
- Choi, Sang-Haeng (Genome Structure Research Laboratory) ;
- Chae, Sung-Hwa (Genome Structure Research Laboratory) ;
- Park, Hong-Seog (Genome Structure Research Laboratory, University of Science and Technology (UST))
- 발행 : 2005.12.01
초록
The immune response-related genes have been suggested to be the most favorable genes for positive selection during evolution. Comparing the entire DNA sequence of chimpanzee chromosome 22 (PTR22) with human chromosome 21 (HSA21), we have identified 15 orthologs having indel in their coding sequences. Among them, interferon-