Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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Hypoglycemic Effects of Propolis to the Streptozotocin Induced Diabetic Rats

Propolis 투여가 Streptozotocin으로 유발된 당뇨병 Rat의 혈당에 미치는 영향

  • Chung, Nyun-Ki (Department of Public Health, Graduate School of Chungnam National University) ;
  • Lee, Dong-Bae (Department of Preventive Medicine and Public Health, College of Medicine, Chungnam National University) ;
  • Cho, Young-Chae (Department of Preventive Medicine and Public Health, College of Medicine, Chungnam National University) ;
  • Ha, Chang-Su (Department of Preventive Medicine and Public Health, College of Medicine, Chungnam National University)
  • 정년기 (충남대학교대학원 보건학과) ;
  • 이동배 (충남대학교 의과대학 예방의학교실) ;
  • 조영채 (충남대학교 의과대학 예방의학교실) ;
  • 하창수 (충남대학교 의과대학 예방의학교실)
  • Published : 2005.03.01
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Abstract

To evaluate the hypoglycemic effect of propolis, streptozotocin (STZ) induced diabetic rats were divided into 4 groups such as, diabetic control group, low dose of propolis (0.1 ml) group, medium dose of propolis (0.3 ml) group and high dose of propolis (0.9 ml) group and feeded with propolis extracts for 30 days. After experiment, oral glucose tolerance test (Oral GTT) was carried, and 16 hours fasting blood sugar levels, body weights, blood lipid levels were measured. Finally, pancreatic histopathological study was performed. In conclusion, the propolis is effective to the treatment diabetes due to the reduction of the blood sugar level and the regeneration of the damaged $\beta$-cells shown in streptozotocininduced diabetic rats.

Keywords

References

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