Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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Minamata Disease and the Mercury Pollution of the Globe

  • Harada Masazumi (Department of Social Welfare Study, Kumamoto Gakuen University)
  • Published : 2005.12.01
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Abstract

Minamata disease made its first appearance in the world at Minamata City, Kumamoto Prefecture, in May 1956. In 1962 methyl mercury poisoning through the placenta was found for the first time in the world. This was called congenital Minamata disease. In all cases the clinical symptoms were consistent with those of cerebral palsy. The time and place of outbreak were the same as those for Minamata disease. Their mothers had eaten fish and shellfish during pregnancy. The principal symptoms of congenital Minamata disease are mentalretardation ($100\%$); primitive reflexes ($100\%$); disturbance of coordination ($100\%$); dysarthria ($100\%$); limb deformation (100%); growth disorders ($100\%$); nutritional disorders ($100\%$); chorea-athetose ($95\%$); and hypersalivation ($95\%$). However, today, when the world is polluted by mercury in various places and at various levels, the data we need is not represented by those severe cases, but rather by the chronic milder type. Even in Minamata, the issue of Minamata disease has not been resolved. And likewise, on a global scale the problem of Minamata disease is not yet over.

Keywords

References

  1. Study Group of Minamata Disease : Minamata Disease, Kumamoto University, Kumamoto, Japan, 1968
  2. Tsubaki, T. and Irukayama, K. : Minamata disease; methylmercury poisoning in Minamata and Niigata. Japan. Amsterdam, Elsevier, 1977
  3. Harada, M. : Minamata Disease (translation edited by Timothy, S. George), Kumamoto, Japan, Kumamoto Nichinichi Shinbun Culture and Information Center, 1972
  4. Harada, M. : Minamata disease, Methylmercury poisoning in Japan caused by environmental pollution. Critical Rev. Toxicol, 25(1), 1-24, 1995 https://doi.org/10.3109/10408449509089885
  5. Harada, M. : Grassroots movements by Minamata victims, International Christian Universitu, Institute of Asia Culture Studies, Asia Culture Studies Special Issue No. 10, 307-311, 1995
  6. Ninomiya, T., Ohmori, Y., Hashimoto, K., Tsuruta, K. and Ekino, S. : Expansion of methylmercury poisoning outside of Minamata, an epidemiological study on chronic methylmercury poisoning outside of Minamata. Environ. Res., 70, 47-50, 1995 https://doi.org/10.1006/enrs.1995.1045
  7. Ninomiya, T., Imamura, K., Kuwahara, M., Kindaichi, M., Susa, M. and Ekino, S. : Reappraisal of somatosennsory disorders .in methylmercury poisoning. Neurotox. Teratol., xx, 5-11, 2005
  8. Harada, M., Nakanishi, J., Konuma, S., Ohno, K., Kimura, Yamaguchi, K., Tsuruta, K., Kizaki, T., Ookawara, T. and Ohono, H. : The present mercury contents of scalp hair and clinical symptoms in inhabitants of the Minamata area. Environ. Rev., 77, 160-164, 1998 https://doi.org/10.1006/enrs.1998.3837
  9. Harada, M. : Intrauterin poisoning, clinical and epidemiological studies and significance of the problem. Bull. Institut. Constitut. Med. Kumamoto University, Suppl., 25, 1-60, 1976
  10. Harada, M. : Congenital Mianmata disease, Intrauterine methylmercury poisoning, Teratogen Update, Environmentally induced birth defect risks (ed. by John L. Sever), 259-265, New York, Aran R., Liss INC, 1986
  11. Nishigaki, S. and Harada, M. : Methylmercury and selenium in umbilical cords of inhabitants of the Minamata area. Nature, 258, 324, 1975
  12. Harada, M., Akagi, H., Tsuda, T., Kizaki, T. and Ohno, H. : Methylmercury level in umbilical cords from patients congenital Minamata disease. Sci. Total Environ., 234, 59-62, 1999 https://doi.org/10.1016/S0048-9697(99)00255-7
  13. Matsumoto, H., Koya, G. and Takeuchi, T. : Fetal Minamata disease ; a neurological study of two cases of intrauterine intoxication by methylmercury compound. J. Neuropathol. Exp. Neurol., 24, 563-574, 1965 https://doi.org/10.1097/00005072-196510000-00002
  14. D'Itri, F.M. : Mercury contamination: what we have learned since Minamata. Environ. Monit. Assess., 19, 165-181, 1991 https://doi.org/10.1007/BF00401309
  15. Harada, M., Fujino, T., Akagi, T. and Nishigaki, S. : Epidemiological and clinical study and hystorical background of mercury pollution on Indian reservations in northwestern Ontario, Canada. Bull. Institut. Constitut. Med. Kumamoto University, 26(3,4), 169-184, 1976
  16. Harada, M., Fujino, T., Akagi, T. and Nishigaki, S. : Mercury contamination in human hair at Indian reservation in Canada. Kumamoto Med. J. 30, 57-64, 1977
  17. Takeuchi, T., D'ltri, F.M., Fisher, P.V., Annett, C.S. and Okabe, M. : The outbreak of Minamata disease (methylmercury poisoning) in cats on Northwestern Ontario reserves. Environ. Research, 13, 215-228, 1977 https://doi.org/10.1016/0013-9351(77)90098-6
  18. Charbonneau, S.M., Munro, L.C., Nera, E.A. and Willes, R.F. : Subacute toxicity of methylmercury in the adult cat. Toxicology Applied Pharmacology, 27, 569-581, 1974 https://doi.org/10.1016/0041-008X(74)90036-2
  19. Harada, M., Hanada, M., Miyakita, T., Fujino, T., Turuda, K., Hukuhara, A., Oorui, T., Nakati, S., Araki, T., Tajiri, M. and Nagano, I. : Study on impacts of long-term mercury contamination in a native Canadian reservation (1975-2004) (in Jap.). Reserch on Environ. Disruption, 34(4), 2-8, 2005
  20. Pan, Y., Jiang, X. and Wang, S. : The problem of methylmercury poisoning along the Songhua River in Chaina, in Proceedings of the international forum on Minamata disease, pp299-304, Minamata, Japan, Nov. 7. 1988
  21. Soong, T.R. : Epidemiological reseaech on the health effect of residents along Sonhua river polluted by methylmercury. in Proceeding of the international symposium on 'Assessment of environment pollution and health effects from methylmercury', pp 164-169, National Instutute for Minamata diseae, WHO, Kumamoto, 1993
  22. Akagi, H., Kinjo, O., Harada, M., Branches, M., Pfeifer, W.C. and Kato, H. : Methylmercury pollution in the Amazon, Brazil, Sci. Total. Environ., 3, 25-32, 1995
  23. Harada, M. : Neurotoxicity of methylmercury, Minamata and the Amazon, Mineral and metal neurotoxicology, pp177-188, (ed. by Yasui, M., Strong, M.J., Ota, K., Verity, M.A.), Boca Raton, CRC Press, 1997
  24. Harada M., Nakanishi, J., Yasoda, E., Maria da Conceicao N. Pinheiro, Oikawa, T., Gereldo de Assis Guimaraes, Bemald da silva Cardoso, Kizaki, T. and Ohno, H. : Mercury pollution in the Tapajos river basin, Amazon , Mercury level of head hair and health effects. Environ. International, 77, 285-290, 2001
  25. Granjean, P., White, P., White, R.F., Debes, F., Araki, S., Yokohama, K., Murata, K., Sorensen, N., Dahl, R. and Jorgensen, P.J. : Cognitive deficit in 7year-old with prenatal exposure to methylmercury. Neurotoxicology and Teratology, 107, 417-428, 1997
  26. International Programme on Chemical Safety (IPCS) : Environmental Criteria, 101, methylmercury, WHO, Geneva, 1990
  27. Harada, M., Nakachi, S., Cheu, T., Hamada, H., Ono, Y., Tsuda, T., Yanagida, K., Kizaki, T. and Ohno, H.: Monitoring of mercury pollution in Tanzania ; relation between head hair mercury and health, Sci. Total Environ., 227, 249-256, 1999 https://doi.org/10.1016/S0048-9697(99)00031-5
  28. Harada, M., Nakachi, S., Tasaka, K., Sakasita, S., Muta, K., Yanagida, K., Doi, R., Kizaki, T. and Ohno, H. : Wide use of skin-lightening soap may cause mercury poisoning in Kenya. Sci. Total Environ. 269, 183-187, 2001 https://doi.org/10.1016/S0048-9697(00)00812-3