Journal of Trauma and Injury

  • 제18권2호
  • /
  • Pages.87-93
  • /
  • 2005
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  • 2799-4317(pISSN)
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  • 2287-1683(eISSN)
대한외상학회 (The Korean Society of Traumatology)
권호 표지

응급센터를 내원한 대퇴골 골절 환자에서 골밀도와 생화학적 표지자들의 의의

Bone Mineral Bensity and Bone Turnover Markers in Patients with Femur Fracture Who Visited the Emergency Department

  • 이경미 (인하대학교 의과대학 응급의학교실) ;
  • 한승백 (인하대학교 의과대학 응급의학교실) ;
  • 김준식 (인하대학교 의과대학 응급의학교실) ;
  • 백광제 (인하대학교 의과대학 응급의학교실) ;
  • 홍성빈 (인하대학교 의과대학 내과학교실) ;
  • 문경호 (인하대학교 의과대학 정형외과학교실) ;
  • 강준순 (인하대학교 의과대학 정형외과학교실) ;
  • 윤승환 (인하대학교 의과대학 신경외과학교실)
  • Lee, Kyoung Mi (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Han, Seung Baik (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Kim, Jun Sig (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Baek, Kwang Je (Department of Emergency Medicine, College of Medicine, Inha University) ;
  • Hong, Seong Bin (Department of Internal Medicine, College of Medicine, Inha University) ;
  • Moon, Kyoung Ho (Department of Orthopedics, College of Medicine, Inha University) ;
  • Kang, Joon Soon (Department of Orthopedics, College of Medicine, Inha University) ;
  • Yoon, Seung-Hwan (Department of Neurosurgery, College of Medicine, Inha University)
  • 투고 : 2005.09.14
  • 심사 : 2005.11.24
  • 발행 : 2005.12.30
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초록

Background: The most frequent fracture seen at the emergency department (ED) in the elderly is a femur fracture whereas they do not know the degree of osteoporosis. We analyzed the degree of osteoporosis in patients with femur fractures and compared patients with only femur fractures (FX) to patients with femur and vertebral fractures (VX) by examining the clinical features, the bone mineral density (BMD), and biochemical markers. Methods: From January 2004 to December 2004, we enrolled prospectively 30 femur fracture patients who visited the ED. The bone mineral densities of the lumbar spine and the femur were examined. Total calcium, phosphate, alkaline phosphatase, osteocalcin, and serum C-terminal telopeptide (s-CTx) were measured. The patients with femur fractures were divided into two subgroups according to the presence of vertebral fracture. Results: All BMDs of the FX group showed osteoporosis. The s-CTx levels were higher than normal. The patients in the FX with VX were older than those in the FX only group, and had lower BMDs. There were no significant differences in markers between the subgroups, but the incidence of trochanteric fractures was higher in FX with VX group than in the FX only group. Conclusion: Femur fractures in the elderly were associated with osteoporosis. In our study, despite a considerable difference in BMD between patients with femur fractures and those with femur fractures combined with vertebral fractures, there was no difference in biochemical markers on bone formation nor in the those of bone resorption. We will further investigate the biochemical markers and BMD in the population of osteoporotic fractures. So those indicators should be helpful for planning treatment and for prevention of FX in the elderly.

키워드

참고문헌

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