The Korean Journal of Pain

The Korean Pain Society (대한통증학회)
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A Treatment of Facial Blushing with Beta Blockade and Antianxiety Drug -A report of two cases-

베타 차단제와 신경안정제를 이용한 안면홍조 환자의 치료경험 -증례 보고-

  • Moon, Jin Cheon (Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine) ;
  • Choi, Seung Ho (Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine) ;
  • Yoon, Kyung Bong (Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine) ;
  • Kim, Won Oak (Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine) ;
  • Yoon, Duck Mi (Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine)
  • 문진천 (연세대학교 의과대학 마취통증의학교실) ;
  • 최승호 (연세대학교 의과대학 마취통증의학교실) ;
  • 윤경봉 (연세대학교 의과대학 마취통증의학교실) ;
  • 김원옥 (연세대학교 의과대학 마취통증의학교실) ;
  • 윤덕미 (연세대학교 의과대학 마취통증의학교실)
  • Received : 2005.09.16
  • Accepted : 2005.12.07
  • Published : 2005.12.10
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Abstract

Facial blushing is a personally disabling condition, which can result in emotional disturbance and be an impediment to social life. Although numerous treatment options exist, including beta blocker, cognitive behavioral therapy and sympathetic neurolysis, no generally accepted form of treatment has been established. Herein, we report two cases of successful reduction of facial blushing following the administration of beta blocker and a minor tranquillizing antianxiety drug.

Keywords

References

  1. Dratt C, Claes G, Olsson-Rex L, Dalman P, Fahlen T, Gorhberg G: Successful treatment of facial blushing by endoscopic transthoracic sympathicotomy. Bt J Derrnarol 1998; 138: 639-43.
  2. Mellander S, Andersson PO, Afzelius LE, Hellstrand P: Neural beta-adrenergic dilatation of the facial vein in man. Possible mechanism in emotional blushing. Acta Physiol Scand 1982; 114: 393-9.
  3. Drummond PD: The effect of adrenergic blockade on blushing and facial flushing. Psychophysiology 1997; 34: 163-8.
  4. Hardman JG, Limbird LE, Gilman AG. Goodman and Gilman's the pharmacological basis of therapeutics: 10th ed. New York, The McGraw-Hill companies. 2001, pp 447-84.
  5. Fabien T, Nilsson HI. Borg K, Humble M, Pauli U: Social Phobia: the clinical efficacy and tolerability of the monoamine oxidase-A and serotonin uptake inhibitor brofaromine, A double-blind placebocontrolled study. Acta Psychiatr Scand 1995; 92: 351-8.
  6. Yuraitis M, Jacob CI: Botulinum toxin for the treatment of facial flushing. Dermarol Surg 2004; 30: 102-4.
  7. Guttuso TJ Jr: Gabapentin's effects on the hot flashes and hypothermia. Neurology 2000; 54: 2161-3.
  8. Shanafelt TD, Barton DL, Adjei AA, Loprinzi CL: Pathophysiology and treatment of hot flashes. Mayo Clin Proc 2002; 77: 1207-18.
  9. Rajesh YS, Prarap CP, Woodyer AB: Thoracoscopic sympathectomy for palmar hyperhidrosis and Raynaud's phenomenon of the upper limb and excessive facial blushing: a five year experience. Postgrad Med J 2002; 78: 682-4.
  10. Neumayer CH, Bischof G, Fugger R, Imhof M, Jakesz R, Plas EG, et al: Efficacy and safety of thoracoscopic sympathicotomy for hyperhydrosis of the upper limb. Results of 734 symphathicotomies. Ann Chir Gynaecol 2001; 90: 195-9.
  11. Edmondson RA, Banerjee AK, Rennie JA: Endoscopic transthoracic sympathectomy in the the treatment of hyperhidrosis. Ann Surg 1992; 215: 289-93.
  12. Neumayer C, Zacher! J, Holak G, Jakesz R, Bischof G: Experience wirh limited endoscopic thoracic sympathetic block for hyperhidrosis and facial blushing. Clin Auton Res 2003; 13(Suppl 1): 152-7.
  13. Drummond PD: A caution about surgical treatment for facial blushing. Br J Derrnarol 2000; 142: 194-5.
  14. Mukens S, de Jong PJ, Dobbelaar A, Bogels SM: Fear of blushing: fearful preoccupation irrespective of facial coloration. Behav Res Ther 1999; 37:1119-28.