마이코플라즈마 폐렴의 임상 역학적 연구(1993-2003년)

Clinico-epidemiologic Study of Mycoplasma pneumoniae Pneumonia(1993 through 2003)

  • 이승현 (가톨릭대학교 의과대학 소아과학교실) ;
  • 노석만 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이경일 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이형신 (가톨릭대학교 의과대학 소아과학교실) ;
  • 홍자현 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이미희 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이준성 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이병철 (가톨릭대학교 의과대학 소아과학교실)
  • Lee, Seung-Hyun (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • No, Suk-Man (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Kyung-Yil (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Hyung-Shin (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Hong, Ja-Hyun (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Mi-Hee (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Joon-Sung (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Byung-Chul (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
  • 투고 : 2004.08.14
  • 심사 : 2004.10.04
  • 발행 : 2005.02.15

초록

목 적 : 1993년부터 2003년까지 발생한 마이코플라즈마 폐렴의 역학적 특성을 알아보고자 하였다. 방 법 : 1993-2003년, 11년 동안 가톨릭대학교 대전성모병원 소아과에 입원한 마이코플라즈마 폐렴 환아 559명을 대상으로 입원기록지를 후향적으로 분석하였다. 성별, 연령별, 연도별, 및 월별 발생에 대해 분석하였으며, 1994년과 2003년의 자료를 비교, 분석하였다. 결 과 : 연간 평균 환아 수는 51명이었으며, 1993-94년, 1997년, 2001년 및 2003년에 많은 환아가 발생하였다. 계절별 발생에서 가을(9-11월)에 233명(41.7%)으로 가장 많이 발생하였으며, 겨울 26.7%, 여름 19.0%, 봄 12.7%을 보였다. 남녀비는 1.2 : 1, 연령은 5-6세를 정점으로 3-8세 사이에 68.2%의 환아가 발생하였다. 1994년과 2003년 비교에서 최고 발생 연령군이 5-6세에서 3-4세로, 2세 미만 발생 환아 비율이 1.1%에서 26%로 최근 유행에서 어린 소아의 이환이 많았다. 1994년에서는 1월을 중심으로한 가을-겨울철 유행을, 2003년에서는 9월을 중심으로 한 여름-가을철 유행을 보였다. 결 론 : 최근 10년간 마이코플라즈마 폐렴의 양상은 2-4년 유행 주기를 보였으며, 전국적인 유행과 일치하였다. 또한 서구에 비해 더 어린 연령의 소아가 감염되고, 최대 발병 연령이 근자에 가까울수록 더 어려지는 경향을 보였다.

Purpose : We evaluated the epidemiologic and clinical characteristics of mycoplasma pneumonia. Methods : A total of 559 medical records of children with mycoplasma pneumonia admitted to The Catholic University of Korea, Daejeon St. Mary's Hospital, were retrospectively analyzed. Results : The mean annual number of cases was 51. There was a higher occurrence in autumn (September-November, 41.7%) and in winter(26.7%). Outbreaks of mycoplasma pneumonia were noted in 1993-94, 1997, 2001, and 2003. The age distribution showed a peak frequency of 5-6 years of age and 68.2 percent of patients were in 3-8 years of age. The male-to-female ratio was 1.2 : 1. In comparison between 1994 and 2003, there was a difference in age distribution with a peak frequency of 5-6 years of age in 1994, and of 3-4 years of age in 2003. There were outbreaks during autumn and winter in 1993-94, and during summer and autumn in 2003. Conclusion : Outbreaks of mycoplasma pneumonia occurred every 2-4 years in Daejeon in accordance with nationwide epidemics during 1993-2003. The peak incidence of age in the recent outbreak was younger than in the outbreak which occurred 10 years ago, and in outbreaks in Western countries.

키워드

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