Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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A Case of Diffuse Panbronchiolitis Developing in Childhood

소아에서 발생한 미만성 범세기관지염 1례

  • You, Jung Hoon (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Hyung Shin (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Kyung Yil (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Hong, Ja Hyun (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Mi Hee (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Byung Cheol (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
  • 유정훈 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이형신 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이경일 (가톨릭대학교 의과대학 소아과학교실) ;
  • 홍자현 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이미희 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이병철 (가톨릭대학교 의과대학 소아과학교실)
  • Received : 2004.08.18
  • Accepted : 2004.09.22
  • Published : 2005.01.15
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Abstract

Diffuse panbronchiolitis(DPB) is a chronic inflammatory airway disease predominantly affecting respiratory bronchioles, with distinct clinicopathological profiles. It was first described in 1966 by Yamanaka et al. The etiology of DPB is not yet clear, and the natural history of the disease is respiratory failure leading to cor pulmonale and ultimately death. But the long-term use of low-dose macrolide has proven to be highly effective in treating patients with DPB. Usual age at diagnosis is over 40. A few cases of DPB have been reported in Korea since 1992 but there have been no reports in children. We experienced a case of DPB in a 12-year-old girl. Therefore, we report the case with a brief review of the related literature.

미만성 범세기관지염은 호흡세기관지의 전층을 침범하는 진행성의 만성 염증성 폐질환으로 주로 40대 이후에 증상이 나타나며, 소아에서는 매우 드문 것으로 되어 있다. 저자들은 수년간의 만성적인 기침과 가래를 주소로 내원한 12세 여아에서 폐결핵으로 치료하였으나 방사선 검사상 호전이 없어, 임상 경과와 고해상도 전산화 단층 검사, 폐기능 검사 및 기관지 조직 검사 등을 통하여 미만성 범세기관지염으로 진단할 수 있었던 증례를 경험 하였기에 문헌 고찰과 함께 보고하는 바이다. 소아에서도 만성 기침과 부비동염의 병력이 있는 환자에서 흉부방사선 검사상 폐결핵이 의심될 때 미만성 범세기관지염도 감별해야 될 질환의 하나로 포함시켜야 할 것으로 생각된다.

Keywords

References

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