Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Studies on the Inhibitory Effect of Eugenia aromaticum Extract on Pancreatic Lipase

  • Kim, Seung-Kyum (Division of Biotechnology, Kangwon National University) ;
  • Kim, Yong-Mu (Division of Biotechnology, Kangwon National University) ;
  • Hong, Mi-Jeong (Division of Biotechnology, Kangwon National University) ;
  • Rhee, Hae-Ik (Division of Biotechnology, Kangwon National University)
  • Published : 2005.06.30
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Abstract

To develop functional food and anti-obesity drug through inhibition of dietary lipid absorption, inhibitory effects of herb extracts on pancreatic lipase were investigated. Due to high yield and simplicity of isolation, lipase inhibitor (ELI) was isolated from ethyl acetate extract of Eugenia aromaticum, which showed highest inhibitory activity, and characterized for development of novel functional material. Stability of ELI at high temperature and low pH was investigated. Results showed ELI is relatively stable under thermal and acidic conditions, reversible, and noncompetitive inhibitor of pancreatic lipase.

Keywords

References

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