Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Therapeutic Effect of Ozone Gas on Bovine Mastitis

젖소 유방염에 대한 오존가스의 치료효과

  • Kwon Hyun-Joo (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Liu Jianzhu (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Jo Sung-Nam (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Song Kun-Ho (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Kim Duck-Hwan (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Jun Moo-Hyung (Laboratory of Veterinary Microbiology, College of Veterinary Medicine, Chungnam National University) ;
  • Cho Sung-Whan (Laboratory of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University) ;
  • Kim Myung-Cheol (Laboratory of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University) ;
  • Yoon Hyo-In (Laboratory of Veterinary Pharmacology, College of Veterinary Medicine, Chungnam National University)
  • 권현주 (충남대학교 수의과대학) ;
  • 유건주 (충남대학교 수의과대학) ;
  • 조성남 (충남대학교 수의과대학) ;
  • 송근호 (충남대학교 수의과대학) ;
  • 김덕환 (충남대학교 수의과대학) ;
  • 전무형 (충남대학교 수의과대학) ;
  • 조성환 (충남대학교 수의과대학) ;
  • 김명철 (충남대학교 수의과대학) ;
  • 윤효인 (충남대학교 수의과대학)
  • Published : 2005.12.01
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Abstract

The potential therapeutic effect of ozone gas on bovine mastitis was investigated. Eighteen quarters from 18 lactating cows with chronic mastitis were included. The 18 quarters were assigned to the control group (treatment with antibiotics for 3 days), experimental group I (0.1 ppm ozone treatment, for 7 days) and experimental group II (1ppm ozone treatment, for 3days). In experimental group I, milk somatic cell counts were lower on day 7 after ozone treatment, compared to the pretreated counts, but were higher than the control counts. In experimental group II, somatic cell counts were significantly decreased (p<0.05) on day 7 compared to the pretreatment counts, and they were lower than the control counts. There were no changes in leukocyte, neutrophil, or lymphocyte numbers, N/L ratios, N/L ratios, or serum total protein in the control and experimental groups. We concluded that ozone gas treatment(1ppm for 3days) might be effective for treatment of bovine mastitis.

오존가스의 젖소 유방염에 대한 치료효과를 구명할 목적으로 본 실험을 수행하였다. 만성유방염에 이환된 비유우 18분방을 대상으로 하였다 실험분방은 대조군(항생제 투여군: norfloxacin 10g/tube, 2회/일, 3일간: 5분방), 실험군 I (오존가스 0.1 ppm, 250m1, 2회/일, 7일간: 5분방) 및 실험군 II(오존가스 1 ppm, 50m1, 2회/일, 3일간: 8분방)로 각각 나누어 공시하였다. 우유 중 체세포수, 혈액충 백혈구수, 호중구수, 림프구수, 호중구/림프구(N/L)비 및 혈청 단백량의 변화를 처치 전 및 처치 후 7일에 각각 비교 검토하였다. 그 결과, 실험군 1에서는 오존가스 주입 후 7일에 주입 전에 비하여 우유 중 체세포수가 감소하였으나 대조군 보다 높은 수치를 나타내었다. 실험군 II에서는 오존가스 주입 후 7일에 주입 전에 비하여 현저한 감소소견을 나타내었으며(p<0.05), 대조군 보다 낮은 수치를 나타내었다. 그러나 대조군 및 실험군 간의 유의성은 인정되지 않았다 또한 말초혈액 백혈구수, 호중구수, 림프구수, N/L비 및 혈청 단백량의 변화에서는 대조군 및 실험군에 있어서 각각 유의한 변화를 나타내지 않았다. 이상의 결과를 종합해 볼 때, 오존가스는 젖소 유방염의 치료에 유효할 것으로 판단된다.

Keywords

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