대한의생명과학회지 (Biomedical Science Letters)
- 제11권3호
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- Pages.319-326
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- 2005
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
A Study on the Mechanism of Oxidative Stress, Screening of Protective Agents and Signal Transduction of Cell Differentiation in Cultured Osteoblast and Osteoclast Damaged by Reactive Oxygen Species
- Park Seung-Taeck (Department of Anatomy, Scool of Medicine, Wonkwang University) ;
- Jeon Seung-Ho (Department of Anatomy, Scool of Medicine, Wonkwang University)
- 발행 : 2005.09.01
초록
It is well known that oxidative stress of reactive oxygen species (ROS) may be a causative factor in the pathenogenesis of bone disorder on osteoblast or osteoclast. The purpose of this study was to evaluate the cytotoxicity of oxidative stress, protective effect of glutamate receptor antagoinst against ROS-induced osteotoxicity, secretion of tumor necrosis factor